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Charles G Plopper

Explore the profile of Charles G Plopper including associated specialties, affiliations and a list of published articles. Areas
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Articles 69
Citations 1005
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Recent Articles
1.
Van Winkle L, Kelty J, Plopper C
Curr Protoc Toxicol . 2017 Feb; 71:24.5.1-24.5.26. PMID: 28146282
This unit focuses on protocols for assessing microenvironment-specific responses in the thoracic lung tissues. Aspects of the entire respiratory system serve as potential targets for candidate toxicants, but each candidate...
2.
Gharib S, Altemeier W, Van Winkle L, Plopper C, Schlesinger S, Buell C, et al.
Am J Respir Cell Mol Biol . 2012 Dec; 48(3):390-6. PMID: 23258229
Matrix metalloproteinase-7 (MMP7) expression is quickly up-regulated after injury, and functions to regulate wound repair and various mucosal immune processes. We evaluated the global transcriptional response of airway epithelial cells...
3.
Avdalovic M, Tyler N, Putney L, Nishio S, Quesenberry S, Singh P, et al.
Anat Rec (Hoboken) . 2012 Aug; 295(10):1707-16. PMID: 22887719
Exposure to oxidant air pollutants in early childhood, with ozone as the key oxidant, has been linked to significant decrements in pulmonary function in young adults and exacerbation of airway...
4.
Carey S, Plopper C, Hyde D, Islam Z, Pestka J, Harkema J
Toxicol Pathol . 2012 May; 40(6):887-98. PMID: 22552393
Satratoxin-G (SG) is a trichothecene mycotoxin of Stachybotrys chartarum, the black mold suggested to contribute etiologically to illnesses associated with water-damaged buildings. We have reported that intranasal exposure to SG...
5.
Carey S, Ballinger C, Plopper C, McDonald R, Bartolucci A, Postlethwait E, et al.
Am J Physiol Lung Cell Mol Physiol . 2010 Dec; 300(2):L242-54. PMID: 21131400
Children chronically exposed to high levels of ozone (O(3)), the principal oxidant pollutant in photochemical smog, are more vulnerable to respiratory illness and infections. The specific factors underlying this differential...
6.
Lee D, Wallis C, Wexler A, Schelegle E, Van Winkle L, Plopper C, et al.
J Appl Physiol (1985) . 2010 Jul; 109(4):1115-24. PMID: 20634362
Increasing numbers of epidemiologic studies associate air pollution exposure in children with decreased lung function development. The objective of this study was to examine the effects of exposure to combustion-generated...
7.
Evans M, Fanucchi M, Plopper C, Hyde D
Anat Rec (Hoboken) . 2010 May; 293(6):947-54. PMID: 20503389
The basement membrane zone (BMZ) appears as three component layers: the lamina lucida, lamina densa, and lamina reticularis. The laminas lucida and densa are present during all stages of development....
8.
Van Winkle L, Baker G, Chan J, Schelegle E, Plopper C
Toxicol Sci . 2010 Apr; 116(1):313-22. PMID: 20403968
Asthma is a leading cause of morbidity in children. Risk factors include chronic exposure to allergens and air pollution. While chronically activated mast cells contribute to the pathophysiology of asthma...
9.
Albertine K, Dahl M, Gonzales L, Wang Z, Metcalfe D, Hyde D, et al.
Am J Physiol Lung Cell Mol Physiol . 2010 Apr; 299(1):L59-72. PMID: 20382748
Neonatal chronic lung disease is characterized by failed formation of alveoli and capillaries, and excessive deposition of matrix elastin, which are linked to lengthy mechanical ventilation (MV) with O(2)-rich gas....
10.
Greeley M, Van Winkle L, Edwards P, Plopper C
Toxicol Sci . 2009 Nov; 113(2):453-67. PMID: 19880587
While the role of trefoil factors (TFF) in the maintenance of epithelial integrity in the gastrointestinal tract is well known, their involvement in wound healing in the conducting airway is...