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Edward N Harris

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Recent Articles
11.
Cabral F, Al-Rahem M, Skaggs J, Thomas T, Kumar N, Wu Q, et al.
iScience . 2021 Nov; 24(11):103337. PMID: 34816100
Lipopolysaccharides (LPSs) cause lethal endotoxemia if not rapidly cleared from blood circulation. Liver sinusoidal endothelial cells (LSEC) systemically clear LPS by unknown mechanisms. We discovered that LPS clearance through LSEC...
12.
Kumar S, Duan Q, Wu R, Harris E, Su Q
Adv Drug Deliv Rev . 2021 Jul; 176:113869. PMID: 34280515
Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease that encompasses a spectrum of pathological conditions, ranging from simple steatosis (NAFL), nonalcoholic steatohepatitis (NASH), fibrosis/cirrhosis which can further progress to...
13.
Harris E
Dent Regist . 2021 Mar; 33(2):78-82. PMID: 33698838
No abstract available.
14.
Harris E
Dent Regist . 2021 Mar; 24(11):493-494. PMID: 33697791
No abstract available.
15.
Ro S, Fay J, Cyuzuzo C, Jang Y, Lee N, Song H, et al.
Front Cell Dev Biol . 2021 Jan; 8:603421. PMID: 33425907
Proper timely management of various external and internal stresses is critical for metabolic and redox homeostasis in mammals. In particular, dysregulation of mechanistic target of rapamycin complex (mTORC) triggered from...
16.
Pandey E, Nour A, Harris E
Front Physiol . 2020 Aug; 11:873. PMID: 32848838
Liver sinusoidal endothelial cells (LSECs) are the most abundant non-parenchymal cells lining the sinusoidal capillaries of the hepatic system. LSECs are characterized with numerous fenestrae and lack basement membrane as...
17.
Harris E, Baker E
Int J Mol Sci . 2020 May; 21(10). PMID: 32429122
Stabilin-2/HARE is the primary clearance receptor for circulating hyaluronan (HA), a polysaccharide found in the extracellular matrix (ECM) of metazoans. HA has many biological functions including joint lubrication, ocular turgor...
18.
Sun X, Harris E
Am J Physiol Cell Physiol . 2020 May; 318(6):C1200-C1213. PMID: 32374676
The liver is the central metabolic hub for carbohydrate, lipid, and protein metabolism. It is composed of four major types of cells, including hepatocytes, endothelial cells (ECs), Kupffer cells, and...
19.
Gopal T, Kumar N, Perriotte-Olson C, Casey C, Donohue Jr T, Harris E, et al.
Am J Physiol Gastrointest Liver Physiol . 2020 Jan; 318(3):G428-G438. PMID: 31928222
Enhanced free fatty acid (FFA) flux from adipose tissue (AT) to liver plays an important role in the development of nonalcoholic steatohepatitis (NASH) and alcohol-associated liver disease (AALD). We determined...
20.
Beck J, Cabral F, Rasineni K, Casey C, Harris E, Stains C
Biochemistry . 2019 Aug; 58(37):3911-3917. PMID: 31433166
The worldwide incidence of fatty liver disease continues to rise, which may account for concurrent increases in the frequencies of more aggressive liver ailments. Given the existence of histologically identical...