Edward E K Baidoo
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Explore the profile of Edward E K Baidoo including associated specialties, affiliations and a list of published articles.
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103
Citations
2062
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Recent Articles
11.
Huang J, Quest A, Cruz-Morales P, Deng K, Pereira J, Van Cura D, et al.
Nature
. 2023 May;
617(7960):403-408.
PMID: 37138074
Biosynthesis is an environmentally benign and renewable approach that can be used to produce a broad range of natural and, in some cases, new-to-nature products. However, biology lacks many of...
12.
Englund E, Schmidt M, Nava A, Lechner A, Deng K, Jocic R, et al.
J Am Chem Soc
. 2023 Apr;
145(16):8822-8832.
PMID: 37057992
Modular polyketide synthases (PKSs) are polymerases that employ α-carboxyacyl-CoAs as extender substrates. This enzyme family contains several catalytic modules, where each module is responsible for a single round of polyketide...
13.
Lankiewicz T, Choudhary H, Gao Y, Amer B, Lillington S, Leggieri P, et al.
Nat Microbiol
. 2023 Mar;
8(4):596-610.
PMID: 36894634
Lignocellulose forms plant cell walls, and its three constituent polymers, cellulose, hemicellulose and lignin, represent the largest renewable organic carbon pool in the terrestrial biosphere. Insights into biological lignocellulose deconstruction...
14.
Di X, Ortega-Alarcon D, Kakumanu R, Iglesias-Fernandez J, Diaz L, Baidoo E, et al.
Plant Commun
. 2022 Dec;
4(3):100512.
PMID: 36575800
Isoprenoids are a very large and diverse family of metabolites required by all living organisms. All isoprenoids derive from the double-bond isomers isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), which...
15.
Lin C, Geiselman G, Liu D, Magurudeniya H, Rodriguez A, Chen Y, et al.
Biotechnol Biofuels Bioprod
. 2022 Dec;
15(1):145.
PMID: 36567331
Background: Lignocellulosic resources are promising feedstocks for the manufacture of bio-based products and bioenergy. However, the inherent recalcitrance of biomass to conversion into simple sugars currently hinders the deployment of...
16.
Wang X, Baidoo E, Kakumanu R, Xie S, Mukhopadhyay A, Lee T
Biotechnol Biofuels Bioprod
. 2022 Dec;
15(1):137.
PMID: 36510293
With the increasing need for microbial bioproduction to replace petrochemicals, it is critical to develop a new industrial microbial workhorse that improves the conversion of lignocellulosic carbon to biofuels and...
17.
Tian Y, Yang M, Lin C, Park J, Wu C, Kakumanu R, et al.
ACS Sustain Chem Eng
. 2022 Nov;
10(43):14391.
PMID: 36343172
[This corrects the article DOI: 10.1021/acssuschemeng.2c01160.].
18.
Lin C, Tian Y, Nelson-Vasilchik K, Hague J, Kakumanu R, Lee M, et al.
Metab Eng Commun
. 2022 Oct;
15:e00207.
PMID: 36188638
Engineering bioenergy crops to accumulate coproducts can increase the value of lignocellulosic biomass and enable a sustainable bioeconomy. In this study, we engineered sorghum with a bacterial gene encoding a...
19.
Sirirungruang S, Ad O, Privalsky T, Ramesh S, Sax J, Dong H, et al.
Nat Chem Biol
. 2022 Jul;
18(8):886-893.
PMID: 35817967
Although natural products and synthetic small molecules both serve important medicinal functions, their structures and chemical properties are relatively distinct. To expand the molecular diversity available for drug discovery, one...
20.
Placido D, Dong N, Amer B, Dong C, Ponciano G, Kahlon T, et al.
Metabolites
. 2022 Apr;
12(4).
PMID: 35448489
Production of natural rubber by (guayule) requires increased yield for economic sustainability. An RNAi gene silencing strategy was used to engineer isoprenoid biosynthesis by downregulation of squalene synthase (SQS), such...