Eduardo Osinaga
Overview
Explore the profile of Eduardo Osinaga including associated specialties, affiliations and a list of published articles.
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56
Citations
955
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Recent Articles
1.
Castro A, Pittini A, Berois N, Faccio R, Miranda P, Mombru A, et al.
Pharmaceutics
. 2025 Feb;
17(2).
PMID: 40006531
: The focus of this study was to prepare and characterize docetaxel (DCX)-loaded lipid/polymer hybrid nanoparticles (LPHNps) functionalized with the monoclonal antibody (mAb) Chi-Tn for a potential active targeting approach...
2.
Victoria S, Castro A, Pittini A, Olivera D, Russo S, Cebrian I, et al.
Int J Biol Macromol
. 2024 Sep;
279(Pt 3):135327.
PMID: 39236955
The immunoregulatory cation channel TMEM176B plays a dual role in tumor immunity. On the one hand, TMEM176B promotes antigen cross-presentation to CD8 T cells by regulating phagosomal pH in dendritic...
3.
Tassano M, Camacho X, Freire T, Perroni C, da Costa V, Cabrera M, et al.
Cancer Biother Radiopharm
. 2024 Jan;
39(5):337-348.
PMID: 38215243
ChiTn, a mouse/human chimeric anti-Tn monoclonal antibody, was radiolabeled with iodine-131 (I) and technetium-99m (Tc) to assess its biodistribution and internalization in Tn-expressing (Tn+) and wild-type (Tn-) LL/2 lung cancer...
4.
Freire T, Landeira M, Giacomini C, Festari M, Pittini A, Cardozo V, et al.
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499361
Lung cancer remains the leading cause of cancer mortality worldwide. Thus, the development of strategies against this type of cancer is of high value. Parasite infections can correlate with lower...
5.
Berois N, Pittini A, Osinaga E
Cancers (Basel)
. 2022 Feb;
14(3).
PMID: 35158915
Aberrant glycosylation is a hallmark of cancer and can lead to changes that influence tumor behavior. Glycans can serve as a source of novel clinical biomarker developments, providing a set...
6.
Fernandez E, Ubillos L, Elgul N, Festari M, Mazal D, Pritsch O, et al.
Cancers (Basel)
. 2021 Nov;
13(22).
PMID: 34830771
Breast cancer is a public health concern and is currently the fifth cause of mortality worldwide. Identification of different biological subtypes is essential for clinical management; therefore, the role of...
7.
da Costa V, van Vliet S, Carasi P, Frigerio S, Garcia P, Croci D, et al.
Cancer Lett
. 2021 Jun;
518:72-81.
PMID: 34144098
Tn is a tumor-associated carbohydrate antigen that constitutes both a diagnostic tool and an immunotherapeutic target. It originates from interruption of the mucin O-glycosylation pathway through defects involving, at least...
8.
Berriel E, Freire T, Chiale C, Rodriguez E, Moron G, Fernandez-Grana G, et al.
Cancer Immunol Immunother
. 2021 May;
70(12):3617-3627.
PMID: 33944981
Echinococcus granulosus is a cestode parasite which causes cystic echinococcosis disease. Previously we observed that vaccination with E. granulosus antigens from human hydatid cyst fluid (HCF) significantly inhibits colon cancer...
9.
Castro A, Berois N, Malanga A, Ortega C, Oppezzo P, Pristch O, et al.
Int J Biol Macromol
. 2021 Apr;
182:806-814.
PMID: 33857513
The aim of this work was to evaluate the physicochemical and biological properties of docetaxel (DCX) loaded chitosan nanocapsules (CS Nc) functionalized with the monoclonal antibody Chi-Tn (CS-PEG-ChiTn mAb Nc)...
10.
Olano C, Lopez V, Freire T, Rodriguez X, Pontet Y, Aleman A, et al.
Rev Gastroenterol Peru
. 2020 Sep;
40(2):127-135.
PMID: 32876628
Background: Evidence indicates that low-grade inflammation can alter gastrointestinal motor and sensory function and might contribute to the genesis of symptoms in IBS. Objective: To examine relationships between IBS, disease...