Edouard Bertrand
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Explore the profile of Edouard Bertrand including associated specialties, affiliations and a list of published articles.
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137
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8137
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Recent Articles
1.
Translation of unspliced retroviral genomic RNA in the host cell is regulated in both space and time
Leon-Diaz F, Chamontin C, Laine S, Socol M, Bertrand E, Mougel M
J Cell Biol
. 2025 Jan;
224(4).
PMID: 39868815
Retroviruses carry a genomic intron-containing RNA with a long structured 5'-untranslated region, which acts either as a genome encapsidated in the viral progeny or as an mRNA encoding the key...
2.
Radulescu O, Grigoriev D, Seiss M, Douaihy M, Lagha M, Bertrand E
Bull Math Biol
. 2024 Dec;
87(1):11.
PMID: 39625575
Many biological and medical questions can be modeled using time-to-event data in finite-state Markov chains, with the phase-type distribution describing intervals between events. We solve the inverse problem: given a...
3.
Hani S, Mercier C, David P, Bertrand E, Desnos T, Nussaume L
Methods Mol Biol
. 2024 Nov;
2875:37-58.
PMID: 39535638
Transcriptional reprogramming plays a key role in a variety of biological processes. Recent advances in RNA imaging techniques have allowed to visualize, in vivo, transcription-related mechanisms in different organisms. The...
4.
Abeza C, Busse P, Paiva A, Chagot M, Schneider J, Robert M, et al.
J Mol Biol
. 2024 Nov;
436(23):168840.
PMID: 39490680
The R2TP chaperone is composed of the RUVBL1/RUVBL2 AAA+ ATPases and two adapter proteins, RPAP3 and PIH1D1. Together with HSP90, it functions in the assembly of macromolecular complexes that are...
5.
Safieddine A, Benassy M, Bonte T, Slimani F, Pourcelot O, Kress M, et al.
Mol Cell
. 2024 Oct;
84(21):4191-4208.e7.
PMID: 39368464
Understanding the dynamics of RNA targeting to membraneless organelles is essential to disentangle their functions. Here, we investigate how P-bodies (PBs) evolve during cell-cycle progression in HEK293 cells. PB purification...
6.
Bellec M, Chen R, Dhayni J, Trullo A, Avinens D, Karaki H, et al.
RNA
. 2024 Jul;
30(10):1374-1394.
PMID: 39060168
Live imaging of translation based on tag recognition by a single-chain antibody is a powerful technique to assess translation regulation in living cells. However, this approach is challenging and requires...
7.
Issa A, Schlotter F, Flayac J, Chen J, Wacheul L, Philippe M, et al.
Life Sci Alliance
. 2024 Jun;
7(8).
PMID: 38858088
The signal recognition particle is essential for targeting transmembrane and secreted proteins to the endoplasmic reticulum. Remarkably, because they work together in the cytoplasm, the SRP and ribosomes are assembled...
8.
Hani S, Mercier C, David P, Desnos T, Escudier J, Bertrand E, et al.
Methods Mol Biol
. 2024 Mar;
2784:87-100.
PMID: 38502480
Single-molecule fluorescence in situ hybridization (smFISH) is a powerful method for the visualization and quantification of individual RNA molecules within intact cells. With its ability to probe gene expression at...
9.
Mazzocca M, Loffreda A, Colombo E, Fillot T, Gnani D, Falletta P, et al.
Nat Commun
. 2023 Oct;
14(1):6433.
PMID: 37833263
Nuclear factors rapidly scan the genome for their targets, but the role of nuclear organization in such search is uncharted. Here we analyzed how multiple factors explore chromatin, combining live-cell...
10.
Damour A, Slaninova V, Radulescu O, Bertrand E, Basyuk E
Viruses
. 2023 Sep;
15(9).
PMID: 37766375
This review summarizes current advances in the role of transcriptional stochasticity in HIV-1 latency, which were possible in a large part due to the development of single-cell approaches. HIV-1 transcription...