Edit Sperling
Overview
Explore the profile of Edit Sperling including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
8
Citations
174
Followers
0
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Recent Articles
1.
Szabo M, Filep C, Nagy M, Sarkozy D, Szigeti M, Sperling E, et al.
J Pharm Biomed Anal
. 2021 Dec;
209:114483.
PMID: 34864596
Omalizumab, a glycoprotein based biotherapeutics, is one of the most frequently used targeted antibody biopharmaceutical to reduce asthma exacerbations, improve lung function and reduce oral corticosteroid use. The effector function...
2.
Lavergne T, Lamichhane R, Malyshev D, Li Z, Li L, Sperling E, et al.
ACS Chem Biol
. 2016 Mar;
11(5):1347-53.
PMID: 26942998
Ribosome assembly has been studied intensively using Förster resonance energy transfer (FRET) with fluorophore-labeled fragments of RNA produced by chemical synthesis. However, these studies are limited by the size of...
3.
Chen S, Sperling E, Silverman J, Davis J, Williamson J
Mol Biosyst
. 2012 Oct;
8(12):3325-34.
PMID: 23090316
The ribosome is an essential organelle responsible for cellular protein synthesis. Until recently, the study of ribosome assembly has been largely limited to in vitro assays, with few attempts to...
4.
Kovacs A, Sperling E, Lazar J, Balogh A, Kadas J, Szekrenyes A, et al.
Electrophoresis
. 2011 Jul;
32(15):1916-25.
PMID: 21732557
mAb proteomics, a reversed biomarker discovery approach, is a novel methodology to recognize the proteins of biomarker potential, but requires subsequent antigen identification steps. While in case of high-abundant proteins,...
5.
Sykes M, Shajani Z, Sperling E, Beck A, Williamson J
J Mol Biol
. 2010 Aug;
403(3):331-45.
PMID: 20709079
Although high-resolution structures of the ribosome have been solved in a series of functional states, relatively little is known about how the ribosome assembles, particularly in vivo. Here, a general...
6.
Sykes M, Sperling E, Chen S, Williamson J
Anal Chem
. 2010 May;
82(12):5038-45.
PMID: 20481440
Relative levels of ribosomal proteins were quantified in crude cell lysates using mass spectrometry. A method for quantifying cellular protein levels using macromolecular standards is presented that does not require...
7.
Sperling E, Bunner A, Sykes M, Williamson J
Anal Chem
. 2008 Jun;
80(13):4906-17.
PMID: 18522437
Quantitative proteomic mass spectrometry involves comparison of the amplitudes of peaks resulting from different isotope labeling patterns, including fractional atomic labeling and fractional residue labeling. We have developed a general...
8.
Hennig M, Scott L, Sperling E, Bermel W, Williamson J
J Am Chem Soc
. 2007 Nov;
129(48):14911-21.
PMID: 17990877
Enzymatic synthesis methods for the fluorinated 5'-triphosphate analogues 5F-UTP and 5F-CTP have been developed to facilitate 19F-labeling of RNAs for biophysical studies. HIV-2 TAR RNAs were synthesized using these analogues...