Eddie James
Overview
Explore the profile of Eddie James including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
774
Followers
0
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Recent Articles
1.
Uenishi G, Repic M, Yam J, Landuyt A, Saikumar-Lakshmi P, Guo T, et al.
JCI Insight
. 2024 Mar;
9(6).
PMID: 38516892
Tregs have the potential to establish long-term immune tolerance in patients recently diagnosed with type 1 diabetes (T1D) by preserving β cell function. Adoptive transfer of autologous thymic Tregs, although...
2.
Carmona-Rivera C, Carlucci P, Goel R, James E, Brooks S, Rims C, et al.
JCI Insight
. 2020 Jun;
5(13).
PMID: 32484790
Rheumatoid arthritis (RA) is characterized by synovial joint inflammation, cartilage damage, and dysregulation of the adaptive immune system. While neutrophil extracellular traps (NETs) have been proposed to play a role...
3.
Wen X, Yang J, James E, Chow I, Reijonen H, Kwok W
Sci Immunol
. 2020 Feb;
5(44).
PMID: 32060144
The () haplotype is linked to dominant protection from type 1 diabetes, but the cellular mechanism for this association is unclear. To address this question, we identified multiple DR1501- and...
4.
Free M, Stember K, Hess J, McInnis E, Lardinois O, Hogan S, et al.
J Autoimmun
. 2019 Aug;
106:102306.
PMID: 31383567
Background: Treatment of autoimmune diseases has relied on broad immunosuppression. Knowledge of specific interactions between human leukocyte antigen (HLA), the autoantigen, and effector immune cells, provides the foundation for antigen-specific...
5.
Ahmed S, Cerosaletti K, James E, Long S, Mannering S, Speake C, et al.
Diabetes
. 2019 Jun;
68(7):1366-1379.
PMID: 31221801
Type 1 diabetes (T1D) results from the progressive destruction of pancreatic β-cells in a process mediated primarily by T lymphocytes. The T1D research community has made dramatic progress in understanding...
6.
Rudulier C, Tonti E, James E, Kwok W, Larche M
Allergy
. 2019 May;
74(11):2157-2166.
PMID: 31077596
Background: Allergen immunotherapy using synthetic peptide T-cell epitopes (Cat-PAD) from the major cat allergen Fel d 1 has been shown, in allergen exposure studies, to significantly reduce symptoms of allergic...
7.
Carmona-Rivera C, Carlucci P, Moore E, Lingampalli N, Uchtenhagen H, James E, et al.
Sci Immunol
. 2017 Jun;
2(10).
PMID: 28649674
Rheumatoid arthritis (RA) is characterized by synovial joint inflammation and by development of pathogenic humoral and cellular autoimmunity to citrullinated proteins. Neutrophil extracellular traps (NETs) are a source of citrullinated...
8.
Clemente-Casares X, Blanco J, Ambalavanan P, Yamanouchi J, Singha S, Fandos C, et al.
Nature
. 2016 Feb;
530(7591):434-40.
PMID: 26886799
Regulatory T cells hold promise as targets for therapeutic intervention in autoimmunity, but approaches capable of expanding antigen-specific regulatory T cells in vivo are currently not available. Here we show...
9.
Chemin K, Pollastro S, James E, Ge C, Albrecht I, Herrath J, et al.
Arthritis Rheumatol
. 2015 Dec;
68(5):1124-35.
PMID: 26713667
Objective: Antibodies against citrullinated type II collagen (Cit-CII) are common in the sera and synovial fluid of patients with rheumatoid arthritis (RA); however, the known T cell epitope of CII...
10.
Long H, Chagoury O, Leese A, Ryan G, James E, Morton L, et al.
J Exp Med
. 2013 Apr;
210(5):933-49.
PMID: 23569328
Virus-specific CD4(+) T cells are key orchestrators of host responses to viral infection yet, compared with their CD8(+) T cell counterparts, remain poorly characterized at the single cell level. Here...