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Eddie James

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Articles 19
Citations 774
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Recent Articles
11.
Yang J, James E, Gates T, DeLong J, LaFond R, Malhotra U, et al.
Int Immunol . 2013 Mar; 25(8):447-57. PMID: 23524391
Influenza A/California/4/2009 (H1N1/09) is a recently emerged influenza virus capable of causing serious illness or death in otherwise healthy individuals. Serious outcomes were most common in young adults and children,...
12.
Faner R, James E, Huston L, Pujol-Borrel R, Kwok W, Juan M
Eur J Immunol . 2009 Oct; 40(1):91-102. PMID: 19830726
In humans, several HLA-DRB loci (DRB1/3/4/5) encode diverse beta-chains that pair with alpha-chains to form DR molecules on the surface of APC. While DRB1 and DRB5 have been extensively studied,...
13.
Yang J, Gebe J, Huston L, James E, Tan V, Yue B, et al.
Vaccine . 2009 May; 27(29):3862-9. PMID: 19446935
CD4+ T cells play a pivotal role in the viral immunity, and as such identification of unique strain-specific HLA class II restricted epitopes is essential for monitoring cellular strain-specific viral...
14.
Long S, Walker M, Rieck M, James E, Kwok W, Sanda S, et al.
Eur J Immunol . 2009 Jan; 39(2):612-20. PMID: 19180473
CD4(+)CD25(+)FOXP3(+) Treg cells require TCR engagement for suppressive function, thus ensuring that suppression occurs only in the presence of specific antigens; however, to date no studies have addressed the function...
15.
Yang J, James E, Roti M, Huston L, Gebe J, Kwok W
Int Immunol . 2008 Dec; 21(1):63-71. PMID: 19050106
Identification of dominant T cell epitopes within newly emerging and re-emerging infectious organisms is valuable in understanding pathogenic immune responses and potential vaccine designs. However, difficulties in obtaining samples from...
16.
Kwok W, Yang J, James E, Bui J, Huston L, Wiesen A, et al.
Infect Immun . 2008 Aug; 76(10):4538-45. PMID: 18678674
Cellular immune responses against protective antigen (PA) of Bacillus anthracis in subjects that received the anthrax vaccine adsorbed (AVA) vaccine were examined. Multiple CD4(+) T-cell epitopes within PA were identified...
17.
Yang J, Danke N, Roti M, Huston L, Greenbaum C, Pihoker C, et al.
J Autoimmun . 2008 Apr; 31(1):30-41. PMID: 18385016
Recent studies suggest that insulin is a primary autoantigen for type 1 diabetes. Several studies have identified preproinsulin (PPI) 76-90 as an immunodominant CD4+ T cell epitope. We developed a...
18.
Laughlin E, Miller J, James E, Fillos D, Ibegbu C, Mittler R, et al.
Infect Immun . 2007 Feb; 75(4):1852-60. PMID: 17283103
Detection of antigen-specific CD4+ T cells is facilitated by the use of fluorescently labeled soluble peptide-major histocompatibility complex (MHC) multimers which mirror the antigen specificity of T-cell receptor recognition. We...
19.
James E, Lee J
Plant Cell Rep . 2006 Feb; 25(7):723-7. PMID: 16501979
This paper addresses the problem of decreasing protein expression levels in genetically modified plant cells. A modeling approach was used to explain the loss of productivity over successive generations. Using...