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Ebbe Toftgaard Poulsen

Explore the profile of Ebbe Toftgaard Poulsen including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 327
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Recent Articles
1.
Mogensen E, Poulsen E, Thogersen I, Yamamoto K, Bruel A, Enghild J
Exp Eye Res . 2022 Apr; 219:109081. PMID: 35461874
The human cornea is responsible for approximately 70% of the eye's optical power and, together with the lens, constitutes the only transparent tissue in the human body. Low-density lipoprotein receptor-related...
2.
Bartas M, Volna A, Beaudoin C, Poulsen E, cerven J, Brazda V, et al.
Brief Bioinform . 2022 Mar; 23(3). PMID: 35229157
SARS-CoV-2 is a novel positive-sense single-stranded RNA virus from the Coronaviridae family (genus Betacoronavirus), which has been established as causing the COVID-19 pandemic. The genome of SARS-CoV-2 is one of...
3.
Nielsen N, Gadeberg T, Poulsen E, Harwood S, Weberskov C, Pedersen J, et al.
J Biol Chem . 2021 Jun; 297(1):100858. PMID: 34097874
Protein aggregation in the outermost layers of the cornea, which can lead to cloudy vision and in severe cases blindness, is linked to mutations in the extracellular matrix protein transforming...
4.
Poulsen E, Lumi X, Hansen A, Enghild J, Petrovski G
Transl Vis Sci Technol . 2020 Oct; 9(11):16. PMID: 33117608
Purpose: To study the proteome of the subretinal fluid (SRF) from rhegmatogenous retinal detachment (RRD) in search for novel markers for improved diagnosis and prognosis of RRD. Methods: Human undiluted...
5.
Dalskov L, Mohlenberg M, Thyrsted J, Blay-Cadanet J, Poulsen E, Folkersen B, et al.
EMBO Rep . 2020 Oct; 21(12):e51252. PMID: 33112036
Respiratory infections, like the current COVID-19 pandemic, target epithelial cells in the respiratory tract. Alveolar macrophages (AMs) are tissue-resident macrophages located within the lung. They play a key role in...
6.
Nielsen N, Poulsen E, Lukassen M, Chao Shern C, Mogensen E, Weberskov C, et al.
Prog Retin Eye Res . 2020 Feb; 77:100843. PMID: 32004730
Transforming growth factor-β-induced protein (TGFBIp), an extracellular matrix protein, is the second most abundant protein in the corneal stroma. In this review, we summarize the current knowledge concerning the expression,...
7.
Poulsen E, Nielsen N, Scavenius C, Mogensen E, Risor M, Runager K, et al.
J Biol Chem . 2019 Jun; 294(31):11817-11828. PMID: 31197037
The serine protease high-temperature requirement protein A1 (HtrA1) is associated with protein-misfolding disorders such as Alzheimer's disease and transforming growth factor β-induced protein (TGFBIp)-linked corneal dystrophy. In this study, using...
8.
Nielsen N, Juhl D, Poulsen E, Lukassen M, Poulsen E, Risor M, et al.
Biochemistry . 2017 Nov; 56(49):6470-6480. PMID: 29140698
Mutations in the transforming growth factor β-induced protein (TGFBIp) cause phenotypically diverse corneal dystrophies, where protein aggregation in the cornea leads to severe visual impairment. Previous studies have shown a...
9.
Poulsen E, Runager K, Nielsen N, Lukassen M, Thomsen K, Snider P, et al.
FEBS J . 2017 Nov; 285(1):101-114. PMID: 29117645
TGFBIp is a constituent of the extracellular matrix in many human tissues including the cornea, where it is one of the most abundant proteins expressed. TGFBIp interacts with Type I,...
10.
Poulsen E, Pedersen K, Marzeda A, Enghild J
Biochemistry . 2017 Jan; 56(6):896-902. PMID: 28098450
The pentraxin serum amyloid P component (SAP) is secreted by the liver and found in plasma at a concentration of approximately 30 mg/L. SAP is a 25 kDa homopentamer known...