E Y Skolnik
Overview
Explore the profile of E Y Skolnik including associated specialties, affiliations and a list of published articles.
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39
Citations
2906
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Recent Articles
1.
Shen B, Liu H, Skolnik E, Manley J
Proc Natl Acad Sci U S A
. 2001 Jul;
98(15):8596-601.
PMID: 11447260
Signaling through the Toll receptor is required for dorsal/ventral polarity in Drosophila embryos, and also plays an evolutionarily conserved role in the immune response. Upon ligand binding, Toll appears to...
2.
Xue Y, Wang X, Li Z, Gotoh N, Chapman D, Skolnik E
Development
. 2001 Apr;
128(9):1559-72.
PMID: 11290295
We have previously shown that the Drosophila Ste20 kinase encoded by misshapen (msn) is an essential gene in Drosophila development. msn function is required to activate the Drosophila c-Jun N-terminal...
3.
Ferguson K, Kavran J, Sankaran V, Fournier E, Isakoff S, Skolnik E, et al.
Mol Cell
. 2000 Sep;
6(2):373-84.
PMID: 10983984
Pleckstrin homology (PH) domains are protein modules of around 120 amino acids found in many proteins involved in cellular signaling. Certain PH domains drive signal-dependent membrane recruitment of their host...
4.
Su Y, Treisman J, Skolnik E
Mol Cell Biol
. 2000 Jun;
20(13):4736-44.
PMID: 10848599
We have previously shown that the Ste20 kinase encoded by misshapen (msn) functions upstream of the c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase module in Drosophila. msn is required to...
5.
Becker E, Huynh-Do U, Holland S, Pawson T, Daniel T, Skolnik E
Mol Cell Biol
. 2000 Feb;
20(5):1537-45.
PMID: 10669731
The mammalian Ste20 kinase Nck-interacting kinase (NIK) specifically activates the c-Jun amino-terminal kinase (JNK) mitogen-activated protein kinase module. NIK also binds the SH3 domains of the SH2/SH3 adapter protein Nck....
6.
Schwenger P, Alpert D, Skolnik E, Vilcek J
J Cell Physiol
. 1999 Mar;
179(1):109-14.
PMID: 10082138
Salicylates inhibit signaling by tumor necrosis factor (TNF), including TNF-induced activation of mitogen-activated protein kinases (MAPKs). On the other hand, we recently showed that in normal human diploid fibroblasts sodium...
7.
Liu H, Su Y, Becker E, Treisman J, Skolnik E
Curr Biol
. 1999 Feb;
9(2):101-4.
PMID: 10021364
Two families of protein kinases that are closely related to Ste20 in their kinase domain have been identified - the p21-activated protein kinase (Pak) and SPS1 families [1-3]. In contrast...
8.
Kavran J, Klein D, Lee A, Falasca M, Isakoff S, Skolnik E, et al.
J Biol Chem
. 1998 Nov;
273(46):30497-508.
PMID: 9804818
Pleckstrin homology (PH) domains are small protein modules involved in recruitment of signaling molecules to cellular membranes, in some cases by binding specific phosphoinositides. We describe use of a convenient...
9.
Isakoff S, Cardozo T, ANDREEV J, Li Z, Ferguson K, Abagyan R, et al.
EMBO J
. 1998 Sep;
17(18):5374-87.
PMID: 9736615
Phosphatidylinositol 3-kinase (PI3K) mediates a variety of cellular responses by generating PtdIns(3,4)P2 and PtdIns(3,4,5)P3. These 3-phosphoinositides then function directly as second messengers to activate downstream signaling molecules by binding pleckstrin...
10.
Su Y, Treisman J, Skolnik E
Genes Dev
. 1998 Aug;
12(15):2371-80.
PMID: 9694801
Dorsal closure in the Drosophila embryo occurs during the later stages of embryogenesis and involves changes in cell shape leading to the juxtaposition and subsequent adherence of the lateral epidermal...