E P Rogakou
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Explore the profile of E P Rogakou including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
5093
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Recent Articles
1.
Mahadevaiah S, Turner J, Baudat F, Rogakou E, de Boer P, Blanco-Rodriguez J, et al.
Nat Genet
. 2001 Mar;
27(3):271-6.
PMID: 11242108
In Saccharomyces cerevisiae, meiotic recombination is initiated by Spo11-dependent double-strand breaks (DSBs), a process that precedes homologous synapsis. Here we use an antibody specific for a phosphorylated histone (gamma-H2AX, which...
2.
Chen H, Bhandoola A, Difilippantonio M, Zhu J, Brown M, Tai X, et al.
Science
. 2000 Dec;
290(5498):1962-5.
PMID: 11110662
Genetic disorders affecting cellular responses to DNA damage are characterized by high rates of translocations involving antigen receptor loci and increased susceptibility to lymphoid malignancies. We report that the Nijmegen...
3.
Paull T, Rogakou E, Yamazaki V, Kirchgessner C, Gellert M, Bonner W
Curr Biol
. 2000 Aug;
10(15):886-95.
PMID: 10959836
Background: The response of eukaryotic cells to double-strand breaks in genomic DNA includes the sequestration of many factors into nuclear foci. Recently it has been reported that a member of...
4.
Rogakou E, Nieves-Neira W, Boon C, Pommier Y, Bonner W
J Biol Chem
. 2000 Mar;
275(13):9390-5.
PMID: 10734083
Histone H2AX is a ubiquitous member of the H2A histone family that differs from the other H2A histones by the presence of an evolutionarily conserved C-terminal motif, -KKATQASQEY. The serine...
5.
Rogakou E, Redon C, Boon C, Johnson K, Bonner W
Biotechniques
. 2000 Jan;
28(1):38-40, 42, 46.
PMID: 10649766
No abstract available.
6.
Rogakou E, Sekeri-Pataryas K
Exp Gerontol
. 1999 Dec;
34(6):741-54.
PMID: 10579635
In a previous communication, we showed that the H2A.1/H2A.2 histone variant ratio decreases in a linear manner during the in vitro aging of human diploid fibroblasts. This ratio is known...
7.
Rogakou E, Boon C, Redon C, Bonner W
J Cell Biol
. 1999 Sep;
146(5):905-16.
PMID: 10477747
The loss of chromosomal integrity from DNA double-strand breaks introduced into mammalian cells by ionizing radiation results in the specific phosphorylation of histone H2AX on serine residue 139, yielding a...
8.
Rogakou E, Pilch D, Orr A, Ivanova V, Bonner W
J Biol Chem
. 1998 Apr;
273(10):5858-68.
PMID: 9488723
When mammalian cell cultures or mice are exposed to ionizing radiation in survivable or lethal amounts, novel mass components are found in the histone H2A region of two-dimensional gels. Collectively...
9.
Rogakou E, Sekeri-Pataryas K
Biochem Biophys Res Commun
. 1993 Nov;
196(3):1274-9.
PMID: 8250883
In this study it is shown that in an in vitro aging cell system of human diploid fibroblasts the ratio of the histone variants H2A.1/H2A.2 decreases in a linear manner...