F Baudat
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Explore the profile of F Baudat including associated specialties, affiliations and a list of published articles.
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8
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1574
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Recent Articles
1.
Baudat F, Buard J, Grey C, Fledel-Alon A, Ober C, Przeworski M, et al.
Science
. 2010 Jan;
327(5967):836-40.
PMID: 20044539
Meiotic recombination events cluster into narrow segments of the genome, defined as hotspots. Here, we demonstrate that a major player for hotspot specification is the Prdm9 gene. First, two mouse...
2.
Mahadevaiah S, Turner J, Baudat F, Rogakou E, de Boer P, Blanco-Rodriguez J, et al.
Nat Genet
. 2001 Mar;
27(3):271-6.
PMID: 11242108
In Saccharomyces cerevisiae, meiotic recombination is initiated by Spo11-dependent double-strand breaks (DSBs), a process that precedes homologous synapsis. Here we use an antibody specific for a phosphorylated histone (gamma-H2AX, which...
3.
Baudat F, Keeney S
Curr Biol
. 2001 Mar;
11(2):R45-8.
PMID: 11231139
Accurate segregation of homologous chromosomes at the first meiotic division requires the tight coordination of DNA replication, homologous recombination and chromosome organization. Recent studies suggest that the initiation of meiotic...
4.
Baudat F, Manova K, Yuen J, Jasin M, Keeney S
Mol Cell
. 2000 Dec;
6(5):989-98.
PMID: 11106739
Spo11, a protein first identified in yeast, is thought to generate the chromosome breaks that initiate meiotic recombination. We now report that disruption of mouse Spo11 leads to severe gonadal...
5.
Mezard C, Baudat F, Debrauwere H, de Massy B, Smith K, Soustelle C, et al.
J Soc Biol
. 2000 Jun;
193(1):23-7.
PMID: 10851552
Recent studies in Saccharomyces cerevisiae have provided new insights in our understanding of the molecular mechanisms of meiotic recombination. Meiosis-specific DNA double-strand breaks have been detected and have been shown...
6.
Keeney S, Baudat F, Angeles M, Zhou Z, Copeland N, Jenkins N, et al.
Genomics
. 1999 Oct;
61(2):170-82.
PMID: 10534402
The Saccharomyces cerevisiae Spo11 protein is thought to catalyze formation of the DNA double-strand breaks that initiate meiotic recombination. We have cloned cDNA and genomic DNA for a mouse gene...
7.
Baudat F, Nicolas A
Proc Natl Acad Sci U S A
. 1997 May;
94(10):5213-8.
PMID: 9144217
In the yeast Saccharomyces cerevisiae, meiotic recombination is initiated by transient DNA double-strand breaks (DSBs) that are repaired by interaction of the broken chromosome with its homologue. To identify a...
8.
de Massy B, Baudat F, Nicolas A
Proc Natl Acad Sci U S A
. 1994 Dec;
91(25):11929-33.
PMID: 7991559
In most eukaryotes during prophase I of meiosis, homologous chromosomes pair and recombine by coordinated molecular and cellular processes. To directly test whether or not the early steps of the...