E M Jarvie
Overview
Explore the profile of E M Jarvie including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
151
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Recent Articles
1.
Effects of neo-adjuvant chemotherapy for oesophago-gastric cancer on neuro-muscular gastric function
Sung E, Arasaradnam R, Jarvie E, James S, Goodyear S, Borman R, et al.
Mol Biol Rep
. 2012 Jun;
39(12):9989-94.
PMID: 22744429
Delayed gastric emptying symptoms are often reported after chemotherapy. This study aims to characterise the effects of chemotherapy on gastric neuro-muscular function. Patients undergoing elective surgery for oesophago-gastric cancer were...
2.
Sanger G, Westaway S, Barnes A, Macpherson D, Muir A, Jarvie E, et al.
Neurogastroenterol Motil
. 2009 Apr;
21(6):657-64, e30-1.
PMID: 19374732
There is an urgent clinical need for a safe, efficacious stimulant of gastric emptying; current therapies include erythromycin (an antibiotic with additional properties which preclude chronic use) and metoclopramide (a...
3.
Bassil A, Borman R, Jarvie E, McArthur-Wilson R, Thangiah R, Sung E, et al.
Br J Pharmacol
. 2008 Mar;
154(1):126-35.
PMID: 18332851
Background And Purpose: Lubiprostone (Amitiza), a possible ClC-2 channel opener derived from prostaglandin E(1) and indicated for the treatment of constipation, increases chloride ion transport and fluid secretion into the...
4.
Cellek S, Thangiah R, Jarvie E, Vivekanandan S, Lalude O, Sanger G
Neurogastroenterol Motil
. 2008 Jan;
20(5):539-45.
PMID: 18194150
5-Hydroxytryptamine (5-HT4) receptor agonists increase gastrointestinal (GI) motility by enhancing enteric acetylcholine release which is then metabolized by acetylcholinesterase (AChE) to inactive metabolites. As both AChE inhibitors and, more usually,...
5.
Jarvie E, North Laidler V, Corcoran S, Bassil A, Sanger G
Br J Pharmacol
. 2007 Jan;
150(4):455-62.
PMID: 17211452
Background And Purpose: Motilin or 5-HT4 receptor agonists stimulate gastrointestinal motility. Differences in activity are suggested but direct comparisons are few. A method was devised to directly compare the gastric...
6.
Cellek S, John A, Thangiah R, Dass N, Bassil A, Jarvie E, et al.
Neurogastroenterol Motil
. 2006 Aug;
18(9):853-61.
PMID: 16918765
Previous studies have demonstrated mixed inhibitory and facilitatory effects of 5-hydroxytryptamine-4 (5-HT(4)) receptor agonists on electrical field stimulation (EFS)-induced responses in human isolated colon. Here we report three types of...
7.
Carruthers A, Sellers L, JENKINS D, Jarvie E, Feniuk W, Humphrey P
Mol Pharmacol
. 2001 May;
59(6):1533-41.
PMID: 11353815
Calcitonin gene-related peptide (CGRP), a potent vasodilator, has been implicated in the pathogenesis of migraine. Its release from adult rat trigeminal neurons in culture was shown to be markedly increased...
8.
Souers A, Rosenquist A, Jarvie E, Ladlow M, Feniuk W, Ellman J
Bioorg Med Chem Lett
. 2001 Jan;
10(24):2731-3.
PMID: 11133079
Constrained analogues 5-7 of the potent and subtype selective somatostatin mimetic 1 were prepared by incorporating conformational constraints into the nine-membered heterocyclic scaffold. Each constrained peptidomimetic showed an altered activity...
9.
Scicinski J, BARKER M, Murray P, Jarvie E
Bioorg Med Chem Lett
. 1999 Feb;
8(24):3609-14.
PMID: 9934480
A series of trisubstituted hydantoins has been prepared by a versatile solid phase route employing primary alcohols, amines and amino acids as the monomeric building blocks. Several compounds showed submicromolar...
10.
Schindler M, Kidd E, Carruthers A, Wyatt M, Jarvie E, Sellers L, et al.
Br J Pharmacol
. 1998 Oct;
125(1):209-17.
PMID: 9776362
1. The mouse somatostatin (SRIF) sst2 receptor exists in two splice variants, sst2(a) and sst2(b), which differ in their intracellular carboxy-termini only. The murine sst2(b) receptor was reported to be...