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E D Saggerson

Explore the profile of E D Saggerson including associated specialties, affiliations and a list of published articles. Areas
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Articles 128
Citations 1207
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Recent Articles
1.
Rodin D, Rodin R, Saggerson E
Biochem Pharmacol . 2010 Mar; 29(5):828-9. PMID: 20227964
No abstract available.
2.
Trickett J, Patel D, Knight B, Saggerson E, Gibbons G, Pease R
J Biol Chem . 2001 Aug; 276(43):39522-32. PMID: 11481320
In the current study, we have determined the cDNA and the genomic sequences of the arylacetamide deacetylase (AADA) gene in mice and rats. The AADA genes in the rat and...
3.
Broadway N, Pease R, Birdsey G, Turner N, Shayeghi M, Saggerson E
Biochem Soc Trans . 2001 May; 29(Pt 2):267-71. PMID: 11356165
Liver microsomes contain two carnitine acyltransferase activities. One of these has properties closely corresponding to those of 88 kDa mitochondrial carnitine palmitoyltransferase-1 (CPT-1). Antisera against CPT-1 cross-react with an 88...
4.
Hamilton C, Saggerson E
Biochem J . 2000 Aug; 350 Pt 1:61-7. PMID: 10926826
(1) Malonyl-CoA is thought to play a signalling role in fuel-selection in cardiac muscle, but the rate at which the concentration of this potential signal can be changed has not...
5.
Broadway N, Gooding J, Saggerson E
Adv Exp Med Biol . 2000 Mar; 466:59-67. PMID: 10709628
No abstract available.
6.
Pease R, Wiggins D, Saggerson E, Tree J, Gibbons G
Biochem J . 1999 Jul; 341 ( Pt 2):453-60. PMID: 10393105
Clones of HepG2 cells were selected that stably express the cDNA for hormone-sensitive lipase (HSL). When cells were cultured in the presence of labelled extracellular oleate, accumulation of labelled fatty...
7.
Alam N, Saggerson E
Biochem J . 1998 Aug; 334 ( Pt 1):233-41. PMID: 9693125
1. Rat soleus strips were incubated with 5 mM glucose, after which tissue metabolites were measured. Alternatively, muscle strips were incubated with 5 mM glucose and 0.2 mM palmitate, and...
8.
SWANTON E, Saggerson E
Biochem J . 1998 Feb; 328 ( Pt 3):913-22. PMID: 9396738
Ca2+-tolerant myocytes were isolated with endogenous triacylglycerol (TAG) stores prelabelled with [3H]palmitate and subsequently incubated for a 1h chase period with [14C]palmitate, 2% albumin and 5mM glucose. Measurements were then...
9.
SWANTON E, Saggerson E
Biochim Biophys Acta . 1997 May; 1346(1):93-102. PMID: 9187307
1. The properties and subcellular distribution of phosphatidate phosphohydrolase (PAP) were studied in rat heart. A Mg2(+)-activated activity (PAP1) which was inhibited by N-ethylmaleimide was found mainly in a 105,000...
10.
Broadway N, Saggerson E
Biochem J . 1997 Mar; 322 ( Pt 2):435-40. PMID: 9065760
We have investigated the extent to which membrane environment affects the catalytic properties of the malonyl-CoA-sensitive carnitine acyltransferase of liver microsomal membranes. Arrhenius-type plots of activity were linear in the...