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E Arner

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Articles 12
Citations 442
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Recent Articles
1.
Andersson D, Arner E, Hogling D, Ryden M, Arner P
Int J Obes (Lond) . 2017 Jun; 41(10):1564-1569. PMID: 28630459
Background/objective: Differences in subcutaneous abdominal adipose tissue (SAT) fat cell size and number (cellularity) are linked to insulin resistance. Men are generally more insulin resistant than women but it is...
2.
Petrus P, Mejhert N, Gao H, Backdahl J, Arner E, Arner P, et al.
Diabetes Metab . 2015 Mar; 41(6):509-12. PMID: 25791133
Aim: Recently, in both human and murine white adipose tissue (WAT), transcription factor early B-cell factor 1 (EBF1) has been shown to regulate adipocyte differentiation, adipose morphology and triglyceride hydrolysis...
3.
Eriksson-Hogling D, Andersson D, Backdahl J, Hoffstedt J, Rossner S, Thorell A, et al.
Int J Obes (Lond) . 2015 Feb; 39(6):893-8. PMID: 25666530
Background: Cross-sectional studies show that white adipose tissue hypertrophy (few, large adipocytes), in contrast to hyperplasia (many, small adipocytes), associates with insulin resistance and increased risk of developing type 2...
4.
Hoffstedt J, Arner E, Wahrenberg H, Andersson D, Qvisth V, Lofgren P, et al.
Diabetologia . 2010 Sep; 53(12):2496-503. PMID: 20830466
Aims/hypothesis: The aim of this study was to determine whether the mean size of fat cells in either visceral or subcutaneous adipose tissue has an impact on the metabolic and...
5.
Thunberg S, Neimert-Andersson T, Cheng Q, Wermeling F, Bergstrom U, Swedin L, et al.
Allergy . 2009 Feb; 64(6):919-26. PMID: 19183417
Background: Defined particles carrying tightly bound allergens at high density have been suggested as alternatives in allergy vaccination. Carbohydrate based particles (CBP), sized 2 microm, provide a platform for covalent...
6.
Tortorella M, Malfait A, Deccico C, Arner E
Osteoarthritis Cartilage . 2001 Aug; 9(6):539-52. PMID: 11520168
Introduction: Cleavage of aggrecan between residues Glu(373)-Ala(374), which is believed to be a key event in aggrecan destruction in arthritic diseases, has been attributed to an enzymatic activity, aggrecanase. Two...
7.
Tortorella M, Pratta M, Liu R, Abbaszade I, Ross H, Burn T, et al.
J Biol Chem . 2000 May; 275(33):25791-7. PMID: 10827174
Aggrecanase-1 (ADAMTS-4) is a member of the a disintegrin and metalloprotease with thrombospondin motifs (ADAMTS) protein family that was recently identified. Aggrecanase-1 is one of two ADAMTS cartilage-degrading enzymes purified...
8.
Tortorella M, Pratta M, Liu R, Austin J, ROSS O, Abbaszade I, et al.
J Biol Chem . 2000 Apr; 275(24):18566-73. PMID: 10751421
Aggrecan, the major proteoglycan of cartilage that provides its mechanical properties of compressibility and elasticity, is one of the first matrix components to undergo measurable loss in arthritic diseases. Two...
9.
Eriksson S, Arner E, Spasokoukotskaja T, Wang L, Karlsson A, Brosjo O, et al.
Adv Enzyme Regul . 1994 Jan; 34:13-25. PMID: 7942271
Deoxynucleoside kinases are key enzymes in deoxyribonucleoside salvage, activating several clinically important chemotherapeutic drugs. The four known kinases, cytosolic thymidine kinase (TK1) and deoxycytidine kinase (dCK) and the mitochondrial thymidine...
10.
Venn G, Nietfeld J, Duits A, Brennan F, Arner E, COVINGTON M, et al.
Arthritis Rheum . 1993 Jun; 36(6):819-26. PMID: 8507225
Objective: To measure levels of cytokines, proteases, and glycosaminoglycans (GAG) in synovial fluid (SF) from the knees of animals with experimental osteoarthritis (OA) and from their contralateral (control) knees, and...