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Dylan C Sarver

Explore the profile of Dylan C Sarver including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
11.
Sarver D, Garcia-Diaz J, Saqib M, Riddle R, Wong G
bioRxiv . 2023 Aug; PMID: 37577461
Genome-wide association studies (GWAS) have identified a large number of candidate genes believed to affect longitudinal bone growth and bone mass. One of these candidate genes, , encodes a poorly...
12.
Sarver D, Xu C, Rodriguez S, Aja S, Jaffe A, Gao F, et al.
Elife . 2023 May; 12. PMID: 37249575
The consequences of aneuploidy have traditionally been studied in cell and animal models in which the extrachromosomal DNA is from the same species. Here, we explore a fundamental question concerning...
13.
Sarver D, Xu C, Rodriguez S, Aja S, Jaffe A, Gao F, et al.
bioRxiv . 2023 Feb; PMID: 36778465
The consequences of aneuploidy have traditionally been studied in cell and animal models in which the extrachromosomal DNA is from the same species. Here, we explore a fundamental question concerning...
14.
Sarver D, Xu C, Velez L, Aja S, Jaffe A, Seldin M, et al.
Mol Metab . 2023 Jan; 68:101666. PMID: 36587842
Objective: Trisomy 21 is one of the most complex genetic perturbations compatible with postnatal survival. Dosage imbalance arising from the triplication of genes on human chromosome 21 (Hsa21) affects multiple...
15.
Sarver D, Xu C, Carreno D, Arking A, Terrillion C, Aja S, et al.
FASEB J . 2022 May; 36(6):e22347. PMID: 35579659
C1q/TNF-related proteins (CTRP1-15) constitute a conserved group of secreted proteins of the C1q family with diverse functions. In vitro studies have shown that CTRP11/C1QL4 can inhibit adipogenesis, antagonize myoblast fusion,...
16.
Sarver D, Xu C, Aja S, Wong G
Am J Physiol Endocrinol Metab . 2022 Apr; 322(6):E480-E493. PMID: 35403439
Secreted proteins of the C1q/TNF-related protein (CTRP) family play diverse functions in different organ systems. In the brain, CTRP14/C1QL1 is required for the proper establishment and maintenance of synapses between...
17.
Arking A, Sarver D, Magge S, Wong G, Wolf R
Horm Res Paediatr . 2022 Feb; 95(1):43-50. PMID: 35172300
Introduction: Pediatric obesity and diabetes has increased over the last several decades. While the role of common adipokines on metabolic parameters has been well studied in adults, the relationship of...
18.
Mishra S, Sadagopan N, Dunkerly-Eyring B, Rodriguez S, Sarver D, Ceddia R, et al.
J Clin Invest . 2021 Oct; 131(21). PMID: 34618683
Central obesity with cardiometabolic syndrome (CMS) is a major global contributor to human disease, and effective therapies are needed. Here, we show that cyclic GMP-selective phosphodiesterase 9A inhibition (PDE9-I) in...
19.
Sarver D, Xu C, Cheng Y, Terrillion C, Wong G
FASEB J . 2021 Oct; 35(11):e21910. PMID: 34610176
C1q/TNF-related protein (CTRP) family comprises fifteen highly conserved secretory proteins with diverse central and peripheral functions. In zebrafish, mouse, and human, CTRP4 is most highly expressed in the brain. We...
20.
Markworth J, Sugg K, Sarver D, Maddipati K, Brooks S
FASEB J . 2021 May; 35(6):e21655. PMID: 34042218
Tendon inflammation has been implicated in both adaptive connective tissue remodeling and overuse-induced tendinopathy. Lipid mediators control both the initiation and resolution of inflammation, but their roles within tendon are...