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Dylan Birchard

Explore the profile of Dylan Birchard including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 221
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Recent Articles
1.
Le Floch A, Nagashima K, Birchard D, Scott G, Ben L, Ajithdoss D, et al.
Sci Transl Med . 2023 Jan; 15(678):eabo0205. PMID: 36630481
The common γ chain (γc; IL-2RG) is a subunit of the interleukin (IL) receptors for the γc cytokines IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. The lack of appropriate neutralizing...
2.
Scott G, Asrat S, Allinne J, Lim W, Nagashima K, Birchard D, et al.
Cytokine . 2022 Dec; 162:156091. PMID: 36481478
Rationale: Type 2 (T2) asthma is characterized by airflow limitations and elevated levels of blood and sputum eosinophils, fractional exhaled nitric oxide, IgE, and periostin. While eosinophils are associated with...
3.
Le Floch A, Allinne J, Nagashima K, Scott G, Birchard D, Asrat S, et al.
Allergy . 2019 Dec; 75(5):1188-1204. PMID: 31838750
Background: Dupilumab, a fully human monoclonal antibody that binds IL-4Rα and inhibits signaling of both IL-4 and IL-13, has shown efficacy across multiple diseases with underlying type 2 signatures and...
4.
Allinne J, Scott G, Lim W, Birchard D, Erjefalt J, Sanden C, et al.
J Allergy Clin Immunol . 2019 Sep; 144(6):1624-1637.e10. PMID: 31562870
Background: Severe inflammatory airway diseases are associated with inflammation that does not resolve, leading to structural changes and an overall environment primed for exacerbations. Objective: We sought to identify and...