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Dwight A Towler

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Articles 82
Citations 3827
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Recent Articles
1.
Towler D
Trends Endocrinol Metab . 2024 Mar; 35(7):648-660. PMID: 38429163
Primary hyperparathyroidism (pHPT) afflicts our aging population with an incidence approaching 50 per 100 000 patient-years at a female:male ratio of ~3:1. Decisions surrounding surgical management are currently driven by...
2.
Behrmann A, Zhong D, Li L, Xie S, Mead M, Sabaeifard P, et al.
Endocrinology . 2023 Dec; 165(2). PMID: 38123514
Wnt16 is expressed in bone and arteries, and maintains bone mass in mice and humans, but its role in cardiovascular physiology is unknown. We show that Wnt16 protein accumulates in...
3.
Sutton N, Malhotra R, St Hilaire C, Aikawa E, Blumenthal R, Gackenbach G, et al.
Arterioscler Thromb Vasc Biol . 2022 Nov; 43(1):15-29. PMID: 36412195
Cardiovascular disease is the most common cause of death worldwide, especially beyond the age of 65 years, with the vast majority of morbidity and mortality due to myocardial infarction and...
4.
Collins M, Marcucci G, Anders H, Beltrami G, Cauley J, Ebeling P, et al.
Nat Rev Endocrinol . 2022 Oct; 19(1):62. PMID: 36253529
No abstract available.
5.
Collins M, Marcucci G, Anders H, Beltrami G, Cauley J, Ebeling P, et al.
Nat Rev Endocrinol . 2022 May; 18(8):473-489. PMID: 35578027
The physiological process of biomineralization is complex and deviation from it leads to a variety of diseases. Progress in the past 10 years has enhanced understanding of the genetic, molecular...
6.
Maalouf N, Chhabra A, Zafereo J, Querry R, Towler D, Thakur U, et al.
JBMR Plus . 2022 Jan; 6(1):e10573. PMID: 35079681
Androgen deprivation therapy (ADT) is a cornerstone of advanced prostate cancer (PCa) therapy. Its use is associated with a loss of bone mineral density (BMD) and a greater risk of...
7.
McElvaine A, Hawkins-Salsbury J, Arora V, Gladwin M, Goldenring J, Huston D, et al.
J Clin Invest . 2021 May; 131(10). PMID: 33998594
No abstract available.
8.
Cosman F, Peterson L, Towler D, Mitlak B, Wang Y, Cummings S
J Clin Endocrinol Metab . 2020 Jul; 105(11). PMID: 32658264
Context: Abaloparatide is a US Food and Drug Administration-approved parathyroid hormone-related peptide analog for treatment of osteoporosis in postmenopausal women at high risk of fracture. Objectives: We assessed the cardiovascular...
9.
Behrmann A, Zhong D, Li L, Cheng S, Mead M, Ramachandran B, et al.
Circ Res . 2020 Mar; 126(10):1363-1378. PMID: 32160132
Rationale: The PTH1R (PTH [parathyroid hormone]/PTHrP [PTH-related protein] receptor) is expressed in vascular smooth muscle (VSM) and increased VSM PTH1R signaling mitigates diet-induced arteriosclerosis in LDLR mice. Objective: To study...
10.
Towler D
JACC Basic Transl Sci . 2019 May; 4(2):144-146. PMID: 31061915
No abstract available.