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Duygu Gezen-Ak

Explore the profile of Duygu Gezen-Ak including associated specialties, affiliations and a list of published articles. Areas
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Articles 59
Citations 944
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Recent Articles
1.
Apaydin B, Camoglu T, Canbek Ozdil Z, Gezen-Ak D, Ege D, Gulsoy M
Biotechnol Appl Biochem . 2024 Sep; 72(1):150-163. PMID: 39228174
Alpha-synuclein oligomers play a crucial role in the early diagnosis of Parkinson's disease (PD). In this study, a mercaptoundecanoic acid (MUA)-capped gold nanorod (GNR)-coated and chitosan (CH)-immobilized fiber optic probe...
2.
Camoglu T, Yurttas Z, Kina U, Akkus Sut P, Sahin F, Dursun E, et al.
ACS Omega . 2024 Apr; 9(15):17185-17194. PMID: 38645348
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder worldwide. According to the Braak hypothesis, the disease spreads along specific neuroanatomical pathways. Studies indicate that fibrillar alpha-synuclein (F-αSyn) can...
3.
Charonnat C, Sanchez-Rodriguez D, Karras S, Gezen-Ak D, Dursun E, Annweiler C
Nutrients . 2024 Mar; 16(6). PMID: 38542767
The vitamin D status diagnosticator (VDSD), a 16-item tool, effectively identifies hypovitaminosis D in healthy older adults and can assist in determining the need for blood tests in this population....
4.
Gilbert L, Bourgeais A, Karras S, Gezen-Ak D, Dursun E, Annweiler C
J Nutr Health Aging . 2024 Mar; 28(4):100205. PMID: 38460211
Objectives: Vitamin D is involved in brain health and function. Our objective was to determine whether vitamin D deficiency was associated with behavioral disorders in geriatric patients. Design: The observational...
5.
Keskin E, Gezen-Ak D, Dursun E
ACS Omega . 2023 Dec; 8(48):45519-45534. PMID: 38075821
Neurodegeneration is a condition in which the neuronal structure and functions are altered with reduced neuronal survival and increased neuronal death in the central nervous system (CNS). Amyloid-β (Aβ) is...
6.
Gezen-Ak D, Dursun E
J Alzheimers Dis . 2023 Sep; 95(4):1273-1299. PMID: 37661883
Vitamin D is a secosteroid hormone exerting neurosteroid-like properties. Its well-known nuclear hormone receptor, and recently proposed as a mitochondrial transcription factor, vitamin D receptor, acts for its primary functions....
7.
Karaaslan Z, Sengul-Yediel B, Yuceer-Korkmaz H, Sanli E, Gezen-Ak D, Dursun E, et al.
Mult Scler Relat Disord . 2023 Aug; 78:104940. PMID: 37603930
Introduction: Antibodies to cell surface proteins of astrocytes have been described in chronic inflammatory demyelinating disorders (CIDD) of the central nervous system including multiple sclerosis (MS) and neuromyelitis optica spectrum...
8.
Gezen-Ak D, Alaylioglu M, Yurttas Z, Camoglu T, Sengul B, Isler C, et al.
J Nutr Biochem . 2023 Mar; 116:109322. PMID: 36963731
Vitamin D receptor (VDR) is an essential transcription factor (TF) synthesized in different cell types. We hypothesized that VDR might also act as a mitochondrial TF. We conducted the experiments...
9.
Karras S, Dursun E, Alaylioglu M, Gezen-Ak D, Pilz S, Annweiler C, et al.
Nutrients . 2022 Sep; 14(18). PMID: 36145176
Background: Vitamin D-binding protein (VDBP) is a vital regulator of optimal vitamin D homeostasis and bioavailability. Apart from its well-documented role as a key component in vitamin D dynamic transfer...
10.
Gezen-Ak D, Yurttas Z, Camolu T, Dursun E
ACS Chem Neurosci . 2022 Sep; 13(19):2803-2812. PMID: 36125124
The amyloid β (Aβ) and the α-synuclein (α-syn) are shown to be translocated into mitochondria. Even though their roles are widely investigated in pathological conditions, information on the presence and...