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Merve Alaylioglu

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Articles 27
Citations 379
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Recent Articles
1.
Alaylioglu M, Keskin E, Yediel B, Dursun E, Ak D
Noro Psikiyatr Ars . 2024 Sep; 67(3):208-212. PMID: 39258131
Introduction: Human neuroblastoma cell line SH-SY5Y is a frequently used experimental cellular model in a variety of neuropsychiatric and neurodegenerative disorders. It is crucial to use a culture protocol that...
2.
Gezen-Ak D, Alaylioglu M, Yurttas Z, Camoglu T, Sengul B, Isler C, et al.
J Nutr Biochem . 2023 Mar; 116:109322. PMID: 36963731
Vitamin D receptor (VDR) is an essential transcription factor (TF) synthesized in different cell types. We hypothesized that VDR might also act as a mitochondrial TF. We conducted the experiments...
3.
Tuysuz B, Alkaya D, Geyik F, Alaylioglu M, Kasap B, Kurugoglu S, et al.
J Med Genet . 2022 Dec; 60(8):819-826. PMID: 36543534
Background: Osteogenesis imperfecta (OI) is a heterogeneous group of inherited disorders characterised by susceptibility to fractures, primarily due to defects in type 1 collagen. The aim of this study is...
4.
Karras S, Dursun E, Alaylioglu M, Gezen-Ak D, Pilz S, Annweiler C, et al.
Nutrients . 2022 Sep; 14(18). PMID: 36145176
Background: Vitamin D-binding protein (VDBP) is a vital regulator of optimal vitamin D homeostasis and bioavailability. Apart from its well-documented role as a key component in vitamin D dynamic transfer...
5.
Karras S, Dursun E, Alaylioglu M, Gezen-Ak D, Al Anouti F, Pilz S, et al.
Nutrients . 2022 Jan; 14(1). PMID: 35010965
Dyshomeostasis of vitamin D-binding protein (VDBP) has been implicated in the pathogenesis of various pregnancy complications, including preeclampsia, preterm birth, gestational diabetes, and adverse metabolic profiles in the offspring. VDBP...
6.
Gonen M, Alaylioglu M, Durcan E, Ozdemir Y, Sahin S, Konukoglu D, et al.
Nutrients . 2021 Nov; 13(11). PMID: 34836309
Background: We aimed to establish an acute treatment protocol to increase serum vitamin D, evaluate the effectiveness of vitamin D3 supplementation, and reveal the potential mechanisms in COVID-19. Methods: We...
7.
Karras S, Dursun E, Alaylioglu M, Gezen-Ak D, Annweiler C, Al Anouti F, et al.
Nutrients . 2021 Sep; 13(9). PMID: 34578960
Recent results indicate that dysregulation of vitamin D-binding protein (VDBP) could be involved in the development of hypovitaminosis D, and it comprises a risk factor for adverse fetal, maternal and...
8.
Yavuz U, Alaylioglu M, Sengul B, Karras S, Gezen-Ak D, Dursun E
In Vitro Cell Dev Biol Anim . 2021 Aug; 57(7):704-714. PMID: 34338991
Vitamin D is a secosteroid hormone mediating its functions via vitamin D receptor (VDR) and an endoplasmic reticulum chaperone, protein disulfide isomerase A3 (PDIA3). From a physiological perspective, there is...
9.
Durmus H, Cakar A, Demirci H, Alaylioglu M, Gezen-Ak D, Dursun E, et al.
Acta Neurol Scand . 2021 Jul; 144(6):640-646. PMID: 34322872
Objectives: Hereditary amyloidogenic transthyretin (ATTRv) amyloidosis is an autosomal dominant disorder caused by mutations of the transthyretin (TTR) gene. The mutant ATTRv protein causes a systemic accumulation of amyloid fibrils...
10.
Samanci B, Bilgic B, Gelisin O, Tepgec F, Guven G, Tufekcioglu Z, et al.
Eur J Neurol . 2021 May; 28(8):2603-2613. PMID: 33969597
Background And Purpose: Nasu-Hakola disease (NHD) is a rare, autosomal recessive disorder characterized by skeletal and neurological symptoms. Behavioral symptoms with cognitive impairment may mimic the behavioral variant of frontotemporal...