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Duc-Hiep Bach

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Citations 1000
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Recent Articles
1.
Liu H, He J, Bagheri-Yarmand R, Li Z, Liu R, Wang Z, et al.
Nat Commun . 2022 Jun; 13(1):3684. PMID: 35760800
Osteolytic destruction is a hallmark of multiple myeloma, resulting from activation of osteoclast-mediated bone resorption and reduction of osteoblast-mediated bone formation. However, the molecular mechanisms underlying the differentiation and activity...
2.
Wang Z, He J, Bach D, Huang Y, Li Z, Liu H, et al.
J Exp Clin Cancer Res . 2022 Jan; 41(1):4. PMID: 34980213
Background: Therapeutic resistance occurs in most patients with multiple myeloma (MM). One of the key mechanisms for MM drug resistance comes from the interaction between MM cells and adipocytes that...
3.
Noh K, Bach D, Choi H, Kim M, Wu S, Pradeep S, et al.
Oncogene . 2020 Nov; 40(2):384-395. PMID: 33149280
Paxillin (PXN), a key component of the focal adhesion complex, has been associated with cancer progression, but the underlying mechanisms are poorly understood. The purpose of this study was to...
4.
Luu T, Bach D, Kim D, Hu R, Park H, Lee S
Anticancer Res . 2020 Apr; 40(4):1855-1866. PMID: 32234873
Background/aim: The resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such as gefitinib or erlotinib, is considered a major challenge in the treatment of patients with non-small cell...
5.
Bach D, Zhang W, Sood A
Cancer Res . 2019 Jul; 79(16):3995-4002. PMID: 31350294
Chromosomal instability (CIN) is one of the major forms of genomic instability in various human cancers and is recognized as a common hallmark of tumorigenesis and heterogeneity. However, some malignant...
6.
Fan Y, Ding H, Kim D, Bach D, Hong J, Xu Y, et al.
Cancers (Basel) . 2019 May; 11(5). PMID: 31060329
Aberrant activation of hepatocyte growth factor (HGF)/c-Met signaling pathway caused by gene amplification or mutation plays an important role in tumorigenesis. Therefore, c-Met is considered as an attractive target for...
7.
Kim D, Bach D, Fan Y, Luu T, Hong J, Park H, et al.
Cell Death Dis . 2019 May; 10(5):361. PMID: 31043587
Acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) has been a major obstacle in the treatment of non-small cell lung cancer (NSCLC) patients. AXL has been reported to...
8.
Bach D, Lee S, Sood A
Mol Ther Nucleic Acids . 2019 Mar; 16:118-129. PMID: 30861414
Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are formed by precursor mRNA back-splicing or skipping events of thousands of genes in eukaryotes as covalently closed...
9.
Huong P, Nguyen L, Nguyen X, Lee S, Bach D
Cancers (Basel) . 2019 Feb; 11(2). PMID: 30791448
Besides the critical functions in hemostasis, thrombosis and the wounding process, platelets have been increasingly identified as active players in various processes in tumorigenesis, including angiogenesis and metastasis. Once activated,...
10.
Bach D, Long N, Luu T, Anh N, Kwon S, Lee S
Int J Mol Sci . 2018 Oct; 19(10). PMID: 30360388
Forkhead box (FOX) proteins are multifaceted transcription factors that are significantly implicated in cancer, with various critical roles in biological processes. Herein, we provide an overview of several key members...