Duarte C Barral
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Explore the profile of Duarte C Barral including associated specialties, affiliations and a list of published articles.
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53
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1592
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Recent Articles
1.
Lopes J, Rodrigues C, Godinho-Santos A, Coelho J, Cabaco L, Barral D, et al.
Int J Pharm
. 2024 Nov;
668:124952.
PMID: 39547473
Melanoma is the most aggressive type of skin cancer and recently approved drugs are often associated with resistance and significant adverse effects. Therefore, the design of more effective and safe...
2.
Huntosova V, Andreana M, Mironov A, Barral D
Front Cell Dev Biol
. 2024 Oct;
12:1493620.
PMID: 39435334
No abstract available.
3.
Neto M, Hall M, Charneca J, Escrevente C, Seabra M, Barral D
J Invest Dermatol
. 2024 Sep;
PMID: 39303907
In the skin, melanin is synthesized by melanocytes within melanosomes and transferred to keratinocytes. After being phagocytosed by keratinocytes, melanin polarizes to supranuclear caps that protect against the genotoxic effects...
4.
Ferreira A, Castanheira P, Escrevente C, Barral D, Barona T
Front Cell Dev Biol
. 2024 Mar;
12:1350097.
PMID: 38533085
Breast cancer (BC) is the most common type of cancer in women, and remains one of the major causes of death in women worldwide. It is now well established that...
5.
Hipolito A, Xavier R, Brito C, Tomas A, Lemos I, Cabaco L, et al.
Biochim Biophys Acta Mol Basis Dis
. 2023 Dec;
1870(2):166983.
PMID: 38070581
Cutaneous melanoma (CM) is the most aggressive skin cancer, showing globally increasing incidence. Hereditary CM accounts for a significant percentage (5-15 %) of all CM cases. However, most familial cases...
6.
Bento-Lopes L, Cabaco L, Charneca J, Neto M, Seabra M, Barral D
Int J Mol Sci
. 2023 Jul;
24(14).
PMID: 37511054
Skin pigmentation ensures efficient photoprotection and relies on the pigment melanin, which is produced by epidermal melanocytes and transferred to surrounding keratinocytes. While the molecular mechanisms of melanin synthesis and...
7.
Cabaco L, Bento-Lopes L, Neto M, Ferreira A, Staubli W, Ramalho J, et al.
JID Innov
. 2022 Sep;
2(5):100139.
PMID: 36090299
Skin pigmentation is imparted by melanin and is crucial for photoprotection against UVR. Melanin is synthesized and packaged into melanosomes within melanocytes and is then transferred to keratinocytes (KCs). Although...
8.
Ribeiro N, Albino M, Ferreira A, Escrevente C, Barral D, Pessoa J, et al.
Int J Mol Sci
. 2022 Jun;
23(12).
PMID: 35743176
Colorectal cancer is the second leading cause of cancer-related mortality. Many current therapies rely on chemotherapeutic agents with poor specificity for tumor cells. The clinical success of cisplatin has prompted...
9.
Cabaco L, Tomas A, Pojo M, Barral D
Front Oncol
. 2022 May;
12:887366.
PMID: 35619912
Skin cancers are among the most common cancers worldwide and are increasingly prevalent. Cutaneous melanoma (CM) is characterized by the malignant transformation of melanocytes in the epidermis. Although CM shows...
10.
Morleo M, Vieira H, Pennekamp P, Palma A, Bento-Lopes L, Omran H, et al.
Autophagy
. 2022 May;
19(1):24-43.
PMID: 35613303
Macroautophagy/autophagy is a self-degradative process necessary for cells to maintain their energy balance during development and in response to nutrient deprivation. Autophagic processes are tightly regulated and have been found...