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Cristina Escrevente

Explore the profile of Cristina Escrevente including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 615
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Recent Articles
1.
Neto M, Hall M, Charneca J, Escrevente C, Seabra M, Barral D
J Invest Dermatol . 2024 Sep; PMID: 39303907
In the skin, melanin is synthesized by melanocytes within melanosomes and transferred to keratinocytes. After being phagocytosed by keratinocytes, melanin polarizes to supranuclear caps that protect against the genotoxic effects...
2.
Ferreira A, Castanheira P, Escrevente C, Barral D, Barona T
Front Cell Dev Biol . 2024 Mar; 12:1350097. PMID: 38533085
Breast cancer (BC) is the most common type of cancer in women, and remains one of the major causes of death in women worldwide. It is now well established that...
3.
Cardoso M, Hall M, Burgoyne T, Fale P, Storm T, Escrevente C, et al.
Invest Ophthalmol Vis Sci . 2023 Aug; 64(11):10. PMID: 37548963
Purpose: To model the in vivo effects of chloroquine on the retinal pigment epithelium in experimentally tractable cell culture systems and determine the effects of mild chloroquine treatment on lysosome...
4.
Ribeiro N, Albino M, Ferreira A, Escrevente C, Barral D, Pessoa J, et al.
Int J Mol Sci . 2022 Jun; 23(12). PMID: 35743176
Colorectal cancer is the second leading cause of cancer-related mortality. Many current therapies rely on chemotherapeutic agents with poor specificity for tumor cells. The clinical success of cisplatin has prompted...
5.
Moreiras H, Bento-Lopes L, Neto M, Escrevente C, Cabaco L, Hall M, et al.
Traffic . 2022 Apr; 23(6):331-345. PMID: 35426185
In the skin epidermis, melanin is produced and stored within melanosomes in melanocytes, and then transferred to keratinocytes. Different models have been proposed to explain the melanin transfer mechanism, which...
6.
Barral D, Staiano L, Guimas Almeida C, Cutler D, Eden E, Futter C, et al.
Traffic . 2022 Mar; 23(5):238-269. PMID: 35343629
Since the discovery of lysosomes more than 70 years ago, much has been learned about the functions of these organelles. Lysosomes were regarded as exclusively degradative organelles, but more recent...
7.
Escrevente C, Falcao A, Hall M, Lopes-da-Silva M, Antas P, Mesquita M, et al.
Invest Ophthalmol Vis Sci . 2021 Jul; 62(9):39. PMID: 34313720
Purpose: We aim to characterize the pathways required for autofluorescent granule (AFG) formation by RPE cells using cultured monolayers. Methods: We fed RPE monolayers in culture with a single pulse...
8.
Escrevente C, Bento-Lopes L, Ramalho J, Barral D
J Cell Sci . 2021 Jun; 134(11). PMID: 34100549
Lysosomes are dynamic organelles, capable of undergoing exocytosis. This process is crucial for several cellular functions, namely plasma membrane repair. Nevertheless, the molecular machinery involved in this process is poorly...
9.
Seixas E, Escrevente C, Seabra M, Barral D
Sci Rep . 2018 Aug; 8(1):12998. PMID: 30158654
Phagocytosis of invading microorganisms by professional phagocytic cells has a central role in innate immunity. However, several microorganisms developed strategies to subvert this process. Previously, we reported that bacteria and...
10.
Encarnacao M, Espada L, Escrevente C, Mateus D, Ramalho J, Michelet X, et al.
J Cell Biol . 2016 Jun; 213(6):631-40. PMID: 27325790
Lysosome exocytosis plays a major role in resealing plasma membrane (PM) disruptions. This process involves two sequential steps. First, lysosomes are recruited to the periphery of the cell and then...