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Drieke Vandamme

Explore the profile of Drieke Vandamme including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 190
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Recent Articles
1.
Chastre J, Francois B, Bourgeois M, Komnos A, Ferrer R, Rahav G, et al.
Crit Care . 2022 Nov; 26(1):355. PMID: 36380312
Background: Ventilator-associated pneumonia caused by Pseudomonas aeruginosa (PA) in hospitalised patients is associated with high mortality. The effectiveness of the bivalent, bispecific mAb MEDI3902 (gremubamab) in preventing PA nosocomial pneumonia...
2.
Ruzin A, Barraud O, Yu L, Francois B, Sanchez-Garcia M, Eggimann P, et al.
J Clin Microbiol . 2022 Jun; 60(7):e0034722. PMID: 35758652
We investigated the performance of the Xpert methicillin-resistant Staphylococcus aureus (MRSA)/S. aureus skin and soft tissue (SSTI) quantitative PCR (qPCR) assay in SAATELLITE, a multicenter, double-blind, phase 2 study of...
3.
Minke B, Vandamme D, Schwarzl T, Kolch W, Martin F
Methods Mol Biol . 2016 Nov; 1501:233-243. PMID: 27796956
RNA sequencing is a technique widely used to identify and characterize gene expression patterns. We demonstrate that this method can be applied to screen expression profiles in mammary epithelial cells...
4.
Kim T, Monsefi N, Song J, von Kriegsheim A, Vandamme D, Pertz O, et al.
J Mol Cell Biol . 2015 Mar; 7(3):242-52. PMID: 25780058
Cancer cell migration enables metastatic spread causing most cancer deaths. Rho-family GTPases control cell migration, but being embedded in a highly interconnected feedback network, the control of their dynamical behavior...
5.
Vandamme D, Herrero A, Al-Mulla F, Kolch W
Crit Rev Oncog . 2015 Jan; 19(6):405-15. PMID: 25597351
The Raf kinase inhibitor protein 1 (RKIP-1) was the first reported endogenous inhibitor of Raf-1-MEK-ERK/MAPK cascade, by interfering with the phosphorylation of MEK by Raf-1. However, RKIP's functions related to...
6.
Kim J, Vandamme D, Kim J, Munoz A, Kolch W, Cho K
PLoS Comput Biol . 2014 Aug; 10(7):e1003763. PMID: 25077791
Biological systems are known to be both robust and evolvable to internal and external perturbations, but what causes these apparently contradictory properties? We used Boolean network modeling and attractor landscape...
7.
Vandamme D, Minke B, Fitzmaurice W, Kholodenko B, Kolch W
Wiley Interdiscip Rev Syst Biol Med . 2013 Nov; 6(1):1-11. PMID: 24214316
The pharmaceutical industry is faced with a range of challenges with the ever-escalating costs of drug development and a drying out of drug pipelines. By harnessing advances in -omics technologies...
8.
Tondeleir D, Lambrechts A, Muller M, Jonckheere V, Doll T, Vandamme D, et al.
Mol Cell Proteomics . 2012 Mar; 11(8):255-71. PMID: 22448045
Vertebrate nonmuscle cells express two actin isoforms: cytoplasmic β- and γ-actin. Because of the presence and localized translation of β-actin at the leading edge, this isoform is generally accepted to...
9.
Vandamme D, Lambert E, Waterschoot D, Cognard C, Vandekerckhove J, Ampe C, et al.
Biochim Biophys Acta . 2009 Apr; 1793(7):1259-71. PMID: 19393268
Nemaline myopathy is a neuromuscular disorder, characterized by muscle weakness and hypotonia and is, in 20% of the cases, caused by mutations in the gene encoding alpha-skeletal muscle actin, ACTA1....
10.
Tondeleir D, Vandamme D, Vandekerckhove J, Ampe C, Lambrechts A
Cell Motil Cytoskeleton . 2009 Mar; 66(10):798-815. PMID: 19296487
The dynamic actin cytoskeleton, consisting of six actin isoforms in mammals and a variety of actin binding proteins is essential for all developmental processes and for the viability of the...