Douglas C Dean
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Explore the profile of Douglas C Dean including associated specialties, affiliations and a list of published articles.
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64
Citations
2062
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Recent Articles
1.
Lee S, Emery D, Vukmanic E, Wang Y, Lu X, Wang W, et al.
Cell Rep
. 2024 Dec;
44(1):115160.
PMID: 39709606
No abstract available.
2.
Jin L, Zhang L, Yan C, Liu M, Dean D, Liu Y
Eye Vis (Lond)
. 2024 Jun;
11(1):20.
PMID: 38822380
The cornea, consisting of three cellular and two non-cellular layers, is the outermost part of the eyeball and frequently injured by external physical, chemical, and microbial insults. The epithelial-to-mesenchymal transition...
3.
Do K, Wang F, Sun X, Zhang Y, Liang W, Liu J, et al.
iScience
. 2024 Apr;
27(5):109694.
PMID: 38660397
ZEB1 is an essential factor in embryonic development. In adults, it is often highly expressed in malignant tumors with low expression in normal tissues. The major biological function of ZEB1...
4.
Lee S, Emery D, Vukmanic E, Wang Y, Lu X, Wang W, et al.
Cell Rep
. 2023 Sep;
42(9):113054.
PMID: 37656622
Most mutations in retinitis pigmentosa (RP) arise in rod photoreceptors, but cone photoreceptors, responsible for high-resolution daylight and color vision, are subsequently affected, causing the most debilitating features of the...
5.
Zhang Y, Do K, Wang F, Lu X, Liu J, Li C, et al.
Commun Biol
. 2023 Apr;
6(1):434.
PMID: 37081200
The cornea is the outmost ocular tissue and plays an important role in protecting the eye from environmental insults. Corneal epithelial wounding provokes pain and fear and contributes to the...
6.
Motovylyak A, Vogt N, Adluru N, Ma Y, Wang R, Oh J, et al.
Aging Brain
. 2023 Mar;
2:100030.
PMID: 36908893
Neurite orientation dispersion and density imaging (NODDI) is an advanced diffusion imaging technique, which can detect more distinct microstructural features compared to conventional Diffusion Tensor Imaging (DTI). NODDI allows the...
7.
Guo Y, Lu X, Chen Y, Clark G, Trent J, Cuatrecasas M, et al.
Cell Rep
. 2022 Oct;
41(1):111452.
PMID: 36198275
Epithelial-mesenchymal transition (EMT) facilitates cancer invasion and is initiated by mesenchyme-driving transcription factors and actin cytoskeletal assembly. We show a cytoplasmic-to-nuclear transport gradient of the EMT transcription factor Zeb1 toward...
8.
Ninneman J, Gretzon N, Stegner A, Lindheimer J, Falvo M, Wylie G, et al.
J Neurosci
. 2022 Jun;
42(28):5605-5616.
PMID: 35697521
Chronic musculoskeletal pain (CMP) is a significant burden for Persian Gulf War Veterans (GWVs), yet the causes are poorly understood. Brain structure abnormalities are observed in GWVs, however relationships with...
9.
Chen Y, Lu X, Gao L, Dean D, Liu Y
Cell Oncol (Dordr)
. 2022 Apr;
45(2):309-321.
PMID: 35404029
Purpose: The mechanism underlying cancer heterogeneity and plasticity remains elusive, in spite of the fact that multiple hypotheses have been put forward. We intended to clarify this heterogeneity in uveal...
10.
Liang W, Zhang Y, Zhou L, Lu X, Finn M, Wang W, et al.
iScience
. 2022 Mar;
25(4):104038.
PMID: 35340433
The cornea is an avascular tissue for vision clarity. Alkali burn could cause severe traumatic damage on the cornea with inflammation and neovascularization (NV), leading to vision reduction and blindness....