Dorothee Schwinge
Overview
Explore the profile of Dorothee Schwinge including associated specialties, affiliations and a list of published articles.
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39
Citations
1166
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Recent Articles
1.
Laschtowitz A, Lindberg E, Liebhoff A, Liebig L, Casar C, Steinmann S, et al.
JHEP Rep
. 2025 Feb;
7(3):101267.
PMID: 39996122
Background & Aims: Primary sclerosing cholangitis (PSC) is a chronic heterogenous cholangiopathy with unknown etiology where chronic inflammation of the bile ducts leads to multifocal biliary strictures and biliary fibrosis...
2.
Gronke K, Nguyen M, Fuhrmann H, Santamaria de Souza N, Schumacher J, Pereira M, et al.
Sci Transl Med
. 2025 Feb;
17(784):eadj6294.
PMID: 39908347
Chronic autoimmune diseases often lead to long-term sequelae and require lifelong immunosuppression because of an incomplete understanding of the triggers and drivers in genetically predisposed patients. Gut bacteria that escape...
3.
Liwinski T, Auer M, Schroder J, Pieknik I, Casar C, Schwinge D, et al.
BMC Med
. 2024 Sep;
22(1):346.
PMID: 39218875
Background: Limited data exists regarding gender-specific microbial alterations during gender-affirming hormonal therapy (GAHT) in transgender individuals. This study aimed to investigate the nuanced impact of sex steroids on gut microbiota...
4.
Poch T, Bahn J, Casar C, Krause J, Evangelakos I, Gilladi H, et al.
Cell Rep Med
. 2024 Jun;
5(7):101620.
PMID: 38901430
Primary sclerosing cholangitis (PSC) is an immune-mediated liver disease of unknown pathogenesis, with a high risk to develop cirrhosis and malignancies. Functional dysregulation of T cells and association with genetic...
5.
Kellerer M, Javed S, Casar C, Will N, Berkhout L, Schwinge D, et al.
Hepatology
. 2024 Mar;
80(4):844-858.
PMID: 38441998
Background And Aims: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by biliary inflammation and fibrosis. We showed an elevated interferon γ response in patients with primary...
6.
Krzikalla D, Laschtowitz A, Leypoldt L, Gottwick C, Averhoff P, Weidemann S, et al.
Cell Mol Gastroenterol Hepatol
. 2023 Sep;
17(1):79-91.
PMID: 37734595
Background & Aims: The liver has a distinct capacity to induce immune tolerance to hepatic antigens. Although liver tolerance can be advantageous for preventing autoimmune and inflammatory diseases, it also...
7.
Song Z, Henze L, Casar C, Schwinge D, Schramm C, Fuss J, et al.
J Leukoc Biol
. 2023 Jul;
114(6):630-638.
PMID: 37437101
Accurately identifying γδ T cells in large single-cell RNA sequencing (scRNA-seq) datasets without additional single-cell γδ T cell receptor sequencing (sc-γδTCR-seq) or CITE-seq (cellular indexing of transcriptomes and epitopes sequencing)...
8.
Gronke K, Nguyen M, Santamaria N, Schumacher J, Yang Y, Sonnert N, et al.
bioRxiv
. 2023 Jul;
PMID: 37425769
One Sentence Summary: Translocating pathobiont promotes human Th17 and IgG3 autoantibody responses linked to disease activity in autoimmune patients.
9.
Sturznickel J, Behler-Janbeck F, Baranowsky A, Schmidt T, Schwinge D, John C, et al.
Sci Rep
. 2022 Oct;
12(1):16491.
PMID: 36192408
Primary sclerosing cholangitis (PSC) is an idiopathic cholestatic liver disease characterized by chronic inflammation and progressive fibrosis of intra- and extrahepatic bile ducts. Osteoporosis is a frequent comorbidity in PSC,...
10.
Brehm T, Ullrich F, Thompson M, Kuchen J, Schwinge D, Spier A, et al.
Vaccines (Basel)
. 2022 Jul;
10(7).
PMID: 35891249
Background: The immunogenicity of different COVID-19 vaccine regimens and combinations in naïve and convalescent individuals has not been formally tested in controlled studies, and real-life observational studies are scarce. Methods:...