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Antonella Carambia

Explore the profile of Antonella Carambia including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 822
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Recent Articles
1.
Krzikalla D, Laschtowitz A, Leypoldt L, Gottwick C, Averhoff P, Weidemann S, et al.
Cell Mol Gastroenterol Hepatol . 2023 Sep; 17(1):79-91. PMID: 37734595
Background & Aims: The liver has a distinct capacity to induce immune tolerance to hepatic antigens. Although liver tolerance can be advantageous for preventing autoimmune and inflammatory diseases, it also...
2.
Lubbering D, Preti M, Schlott L, Schultheiss C, Weidemann S, Lohse A, et al.
Immunology . 2023 May; 170(2):214-229. PMID: 37243425
Autoreactive B cells are considered pathogenic drivers in many autoimmune diseases; however, it is not clear whether autoimmune B cells are invariably pathogenic or whether they can also arise as...
3.
Giannou A, Kempski J, Shiri A, Lucke J, Zhang T, Zhao L, et al.
Immunity . 2023 Jan; 56(1):125-142.e12. PMID: 36630911
During metastasis, cancer cells invade, intravasate, enter the circulation, extravasate, and colonize target organs. Here, we examined the role of interleukin (IL)-22 in metastasis. Immune cell-derived IL-22 acts on epithelial...
4.
Horvatits T, Tamminga M, Liu B, Sebode M, Carambia A, Fischer L, et al.
EBioMedicine . 2022 Jul; 82:104147. PMID: 35835713
Background: The contamination of ecosystem compartments by microplastics (MPs) is an ubiquitous problem. MPs have been observed in mice tissues, and recently in human blood, stool and placenta. However, two...
5.
Muller A, Casar C, Preti M, Krzikalla D, Gottwick C, Averhoff P, et al.
J Hepatol . 2022 Jul; 77(6):1532-1544. PMID: 35798133
Background & Aims: Primary sclerosing cholangitis (PSC) is a progressive cholangiopathy characterised by fibrotic stricturing and inflammation of bile ducts, which seems to be driven by a maladaptive immune response...
6.
Gottwick C, Carambia A, Herkel J
Semin Immunopathol . 2022 May; 44(4):475-484. PMID: 35513495
Autoimmune diseases develop when the adaptive immune system attacks the body's own antigens leading to tissue damage. At least 80 different conditions are believed to have an autoimmune aetiology, including...
7.
Carambia A, Schuran F
Semin Immunopathol . 2021 Jun; 43(4):563-575. PMID: 34075438
The aryl hydrocarbon receptor (AHR) is a ubiquitously expressed ligand-activated transcription factor with multifaceted physiological functions. In the immune system, AHR has been unequivocally identified as a key regulatory factor...
8.
Preti M, Schlott L, Lubbering D, Krzikalla D, Muller A, Schuran F, et al.
JCI Insight . 2021 Feb; 6(6). PMID: 33600378
The liver is an immune-privileged organ that can deactivate autoreactive T cells. Yet in autoimmune hepatitis (AIH), autoreactive T cells can defy hepatic control and attack the liver. To elucidate...
9.
Carambia A, Gottwick C, Schwinge D, Stein S, Digigow R, Seleci M, et al.
Immunology . 2020 Dec; 162(4):452-463. PMID: 33346377
Autoimmune diseases are caused by adaptive immune responses to self-antigens. The development of antigen-specific therapies that suppress disease-related, but not unrelated immune responses in general, is an important goal of...
10.
Stein S, Henze L, Poch T, Carambia A, Krech T, Preti M, et al.
J Hepatol . 2020 Nov; 74(4):919-930. PMID: 33197512
Background & Aims: IL-17A-producing T cells are present in autoimmune cholestatic liver diseases; however, little is known about the contribution of IL-17 to periductal immune responses. Herein, we investigated the...