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Doris Chen

Explore the profile of Doris Chen including associated specialties, affiliations and a list of published articles. Areas
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Articles 57
Citations 4742
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Recent Articles
1.
Sun J, Peter A, He J, Tsien J, Zhang H, Cagan D, et al.
Science . 2025 Mar; :eadu6406. PMID: 40048551
No abstract available.
2.
Chen D, Xaver M, Klein F
Methods Mol Biol . 2024 Sep; 2856:401-418. PMID: 39283465
This chapter describes the computational pipeline for the processing and visualization of Protec-Seq data, a method for purification and genome-wide mapping of double-stranded DNA protected by a specific protein at...
3.
Samanta S, Akhter F, Xue R, Sosunov A, Wu L, Chen D, et al.
Brain . 2024 Jul; 148(1):262-275. PMID: 39001866
Mitochondrial and synaptic dysfunction are pathological features of brain ageing and cognitive decline. Synaptic mitochondria are vital for meeting the high energy demands of synaptic transmission. However, little is known...
4.
Wang Y, Bi C, Kawamata Y, Grant L, Samp L, Richardson P, et al.
Nat Chem . 2024 May; 16(9):1539-1545. PMID: 38769366
Electrophilic halogenation is a widely used tool employed by medicinal chemists to either pre-functionalize molecules for further diversity or incorporate a halogen atom into drugs or drug-like compounds to solve...
5.
Aithal R, Nangalia K, Spirek M, Chen D, Klein F, Krejci L
Nucleic Acids Res . 2024 Feb; 52(8):4328-4343. PMID: 38407383
Meiotic recombination is of central importance for the proper segregation of homologous chromosomes, but also for creating genetic diversity. It is initiated by the formation of double-strand breaks (DSBs) in...
6.
Chen D, Gonzales E, Winget M, Shaw J, Artandi M, Tsai S, et al.
J Telemed Telecare . 2024 Jan; :1357633X231224094. PMID: 38254267
Introduction: Little is known about which conditions seen in primary care are appropriate for video visits. This study evaluated video visits compared to office visits for six conditions: abdominal pain,...
7.
Samanta S, Akhter F, Roy A, Chen D, Turner B, Wang Y, et al.
Brain . 2023 Dec; 147(5):1710-1725. PMID: 38146639
Mitochondrial dysfunction is an early pathological feature of Alzheimer disease and plays a crucial role in the development and progression of Alzheimer's disease. Strategies to rescue mitochondrial function and cognition...
8.
Benrimoh D, Fisher V, Seabury R, Sibarium E, Mourgues C, Chen D, et al.
Schizophr Bull . 2023 Oct; 50(2):349-362. PMID: 37830405
Background: There is increasing evidence that people with hallucinations overweight perceptual beliefs relative to incoming sensory evidence. Past work demonstrating prior overweighting has used simple, nonlinguistic stimuli. However, auditory hallucinations...
9.
Breitenecker K, Hedrich V, Pupp F, Chen D, Reznickova E, Ortmayr G, et al.
Front Oncol . 2023 Sep; 13:1238883. PMID: 37746265
Introduction: Hepatocellular carcinoma (HCC) patients at advanced stages receive immunotherapy or treatment with tyrosine kinase inhibitors (TKIs) such as Sorafenib (Sora) or Lenvatinib in frontline as well as Regorafenib (Rego)...
10.
Utukuri P, Shih R, Ajam A, Callahan K, Chen D, Dunkle J, et al.
J Am Coll Radiol . 2023 May; 20(5S):S70-S93. PMID: 37236753
Headache is an ancient problem plaguing a large proportion of the population. At present, headache disorders rank third among the global causes of disability, accounting for over $78 billion per...