Dong Bo Li
Overview
Explore the profile of Dong Bo Li including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
130
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Recent Articles
1.
Li D, Rogers-Evans M, Carreira E
Org Lett
. 2013 Sep;
15(18):4766-9.
PMID: 23991674
New classes of thia/oxa-azaspiro[3.4]octanes are synthesized through the implementation of robust and step-economic routes. The targeted spirocycles have been designed to act as novel, multifunctional, and structurally diverse modules for...
2.
Li D, Rogers-Evans M, Carreira E
Org Lett
. 2011 Oct;
13(22):6134-6.
PMID: 22007769
Step-economic and scalable syntheses of novel thia-azaspiro[3.4]octanes are reported. These spirocycles and some related intermediates can serve as uncharted multifunctional modules for drug discovery chemistry.
3.
Nilewski C, Deprez N, Fessard T, Li D, Geisser R, Carreira E
Angew Chem Int Ed Engl
. 2011 Jul;
50(34):7940-3.
PMID: 21744447
No abstract available.
4.
Li D, Woithe K, Geib N, Abou-Hadeed K, Zerbe K, Robinson J
Methods Enzymol
. 2009 Apr;
458:487-509.
PMID: 19374995
Oxidative phenol cross-linking reactions play a key role in the biosynthesis of glycopeptide antibiotics such as vancomycin. The vancomycin aglycone contains three cross-links between aromatic amino acid side-chains, which stabilize...
5.
Geib N, Woithe K, Zerbe K, Li D, Robinson J
Bioorg Med Chem Lett
. 2007 Dec;
18(10):3081-4.
PMID: 18068978
OxyB catalyzes the first oxidative phenol coupling reaction in vancomycin biosynthesis. OxyB is a P450 hemoprotein whose activity is strictly dependent upon the presence of molecular oxygen. Here, it was...
6.
Okitsu S, Boato F, Mueller M, Li D, Vogel D, Westerfeld N, et al.
Peptides
. 2007 Sep;
28(10):2051-60.
PMID: 17875342
Serine repeat antigen-5 (SERA5) is a candidate antigen for inclusion into a malaria subunit vaccine. During merozoite release and reinvasion the 120 kDa SERA5 precursor protein (P120) is processed, and...
7.
Woithe K, Geib N, Zerbe K, Li D, Heck M, Fournier-Rousset S, et al.
J Am Chem Soc
. 2007 May;
129(21):6887-95.
PMID: 17477533
OxyB is a cytochrome P450 enzyme that catalyzes the first phenol coupling reaction during the biosynthesis of vancomycin-like glycopeptide antibiotics. The phenol coupling reaction occurs on a linear peptide intermediate...
8.
Nicolaou K, Zou B, Dethe D, Li D, Chen D
Angew Chem Int Ed Engl
. 2006 Oct;
45(46):7786-92.
PMID: 17061302
No abstract available.
9.
Li D, Robinson J
Org Biomol Chem
. 2005 Mar;
3(7):1233-9.
PMID: 15785812
The biosynthesis of the vancomycin aglycone involves three oxidative phenol coupling reactions, each catalyzed by a discrete cytochrome P450-like enzyme. Studies on the mechanism and specificity of the enzyme (called...
10.
Zerbe K, Woithe K, Li D, Vitali F, Bigler L, Robinson J
Angew Chem Int Ed Engl
. 2004 Dec;
43(48):6709-13.
PMID: 15593150
No abstract available.