Dmitry V Bulavin
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Explore the profile of Dmitry V Bulavin including associated specialties, affiliations and a list of published articles.
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5501
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Recent Articles
21.
Tarulli G, De Silva D, Ho V, Kunasegaran K, Ghosh K, Tan B, et al.
Breast Cancer Res
. 2013 Feb;
15(1):R10.
PMID: 23369183
Introduction: The molecular circuitry of different cell types dictates their normal function as well as their response to oncogene activation. For instance, mice lacking the Wip1 phosphatase (also known as...
22.
Fernandez F, Soon I, Li Z, Kuan T, Min D, Wong E, et al.
Cell Adh Migr
. 2012 Sep;
6(4):333-43.
PMID: 22983193
Dendritic spine morphology is modulated by protein kinase p38, a mitogen-activated protein (MAPK), in the hippocampus. Protein p38MAPK is a substrate of wip1, a protein phosphatase. The role of wip1...
23.
Brichkina A, Bulavin D
Autophagy
. 2012 Aug;
8(10):1545-7.
PMID: 22895013
Atherosclerosis commonly causes coronary and cerebrovascular diseases, which are major morbidities worldwide. Controlling these conditions remains a challenge owing to an incomplete understanding of underlying molecular mechanisms. We have recently...
24.
Le Guezennec X, Brichkina A, Huang Y, Kostromina E, Han W, Bulavin D
Cell Metab
. 2012 Jul;
16(1):68-80.
PMID: 22768840
Obesity and atherosclerosis-related diseases account for over one-third of deaths in the western world. Controlling these conditions remains a major challenge due to an incomplete understanding of the molecular pathways...
25.
Zhu Y, Bulavin D
Prog Mol Biol Transl Sci
. 2012 Feb;
106:307-25.
PMID: 22340722
Spatial and temporal regulation of protein phosphorylation is key to the control of different molecular networks. This regulation is achieved in part through dephosphorylation of numerous signaling molecules, and emerging...
26.
Goloudina A, Tanoue K, Hammann A, Fourmaux E, Le Guezennec X, Bulavin D, et al.
Proc Natl Acad Sci U S A
. 2011 Nov;
109(2):E68-75.
PMID: 22065775
The inactivation of the p53 tumor suppressor pathway in many cancers often increases their resistance to anticancer therapy. Here we show that a previously proposed strategy directed to Wip1 inhibition...
27.
Cha H, Lowe J, Li H, Lee J, Belova G, Bulavin D, et al.
Cancer Res
. 2010 May;
70(10):4112-22.
PMID: 20460517
The integrity of DNA is constantly challenged throughout the life of a cell by both endogenous and exogenous stresses. A well-organized rapid damage response and proficient DNA repair, therefore, become...
28.
Le Guezennec X, Bulavin D
Trends Biochem Sci
. 2009 Nov;
35(2):109-14.
PMID: 19879149
The PP2C family serine/threonine phosphatase WIP1 is characterized by distinctive oncogenic properties mediated by inhibitory functions on several tumor suppressor pathways, including ATM, CHK2, p38MAPK and p53. PPM1D, the gene...
29.
Wong E, Le Guezennec X, Demidov O, Marshall N, Wang S, Krishnamurthy J, et al.
Dev Cell
. 2009 Jul;
17(1):142-9.
PMID: 19619499
Aging is a complex organismal process that is controlled by genetic, environmental, and behavioral factors. Accumulating evidence supports a role for different cell cycle inhibitors in mammalian aging. Little is...
30.
Zhu Y, Zhang C, Lu L, Demidov O, Sun L, Yang L, et al.
Stem Cells
. 2009 Jun;
27(6):1433-42.
PMID: 19489034
Continual generation of new neural cells from adult neural stem/progenitor cells (NPCs) is an important component of life-long brain plasticity. However, the intrinsic regulation of this process remains poorly defined....