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Dmitry V Bulavin

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Articles 53
Citations 5501
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Recent Articles
11.
Cortez I, Bulavin D, Wu P, McGrath E, Cunningham K, Wakamiya M, et al.
Behav Brain Res . 2016 Oct; 322(Pt B):212-222. PMID: 27765672
A major aspect of mammalian aging is the decline in functional competence of many self-renewing cell types, including adult-born neuronal precursors. Since age-related senescence of self-renewal occurs simultaneously with chronic...
12.
Filipponi D, Muller J, Emelyanov A, Bulavin D
Cancer Cell . 2016 Aug; 30(2):361-362. PMID: 27505679
No abstract available.
13.
Klionsky D, Abdelmohsen K, Abe A, Abedin M, Abeliovich H, Arozena A, et al.
Autophagy . 2016 Jan; 12(1):1-222. PMID: 26799652
No abstract available.
14.
Papaconstantinou J, Wang C, Zhang M, Yang S, Deford J, Bulavin D, et al.
Aging (Albany NY) . 2015 Oct; 7(9):718-33. PMID: 26423835
Functional competence and self-renewal of mammalian skeletal muscle myofibers and progenitor cells declines with age. Progression of the muscle aging phenotype involves the decline of juvenile protective factorsi.e., proteins whose...
15.
Huang Y, Bulavin D
Oncotarget . 2014 Jul; 5(14):5808-18. PMID: 25071020
Oncogene-mediated cellular transformation is a multistep process involving activation of growth-promoting pathways as well as inactivation of tumor suppressors. We recently found that ISGylation of the p53 tumor suppressor is...
16.
Zhu Y, Demidov O, Goh A, Virshup D, Lane D, Bulavin D
J Clin Invest . 2014 Jun; 124(7):3263-73. PMID: 24911145
The number of newly formed neurons declines rapidly during aging, and this decrease in neurogenesis is associated with decreased function of neural stem/progenitor cells (NPCs). Here, we determined that a...
17.
Huang Y, Wee S, Gunaratne J, Lane D, Bulavin D
Cell Cycle . 2014 May; 13(14):2200-10. PMID: 24844324
Degradation of p53 is a cornerstone in the control of its functions as a tumor suppressor. This process is attributed to ubiquitin-dependent modification of p53. In addition to polyubiquitination, we...
18.
Filipponi D, Muller J, Emelyanov A, Bulavin D
Cancer Cell . 2013 Oct; 24(4):528-41. PMID: 24135283
Wip1 phosphatase is emerging as an important regulator of tumorigenesis, but no unifying mechanistic network has been proposed. We found that Wip1 plays a key role in the transcriptional regulation...
19.
Dudgeon C, Shreeram S, Tanoue K, Mazur S, Sayadi A, Robinson R, et al.
Cell Cycle . 2013 Aug; 12(16):2656-64. PMID: 23907125
The Wip1 phosphatase is an oncogene that is overexpressed in a variety of primary human cancers. We were interested in identifying genetic variants that could change Wip1 activity. We identified...
20.
Zhu Y, Huang Y, Kek C, Bulavin D
Cell Stem Cell . 2013 Feb; 12(3):298-303. PMID: 23415913
Emerging lineage-tracing data support the existence of several pools of intestinal stem cells (ISCs) in the adult mouse. The +4 location is known to harbor proliferative cells undergoing robust apoptosis...