Dmitry Shungin
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Explore the profile of Dmitry Shungin including associated specialties, affiliations and a list of published articles.
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40
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Recent Articles
1.
Patel A, Gill D, Shungin D, Mantzoros C, Knudsen L, Bowden J, et al.
Genet Epidemiol
. 2024 Feb;
48(4):151-163.
PMID: 38379245
Phenotypic heterogeneity at genomic loci encoding drug targets can be exploited by multivariable Mendelian randomization to provide insight into the pathways by which pharmacological interventions may affect disease risk. However,...
2.
Ma S, Shungin D, Mallick H, Schirmer M, Nguyen L, Kolde R, et al.
Genome Biol
. 2022 Oct;
23(1):208.
PMID: 36192803
Microbiome studies of inflammatory bowel diseases (IBD) have achieved a scale for meta-analysis of dysbioses among populations. To enable microbial community meta-analyses generally, we develop MMUPHin for normalization, statistical meta-analysis,...
3.
Fedotkina O, Luk A, Jain R, Prasad R, Shungin D, Simo-Servat O, et al.
Acta Ophthalmol
. 2021 Jun;
100(2):e539-e545.
PMID: 34169655
Purpose: Intrauterine undernutrition is associated with increased risk of type 2 diabetes. Children born premature or small for gestational age were reported to have abnormal retinal vascularization. However, whether intrauterine...
4.
Lagou V, Magi R, Hottenga J, Grallert H, Perry J, Bouatia-Naji N, et al.
Nat Commun
. 2021 Feb;
12(1):995.
PMID: 33558525
No abstract available.
5.
Lagou V, Magi R, Hottenga J, Grallert H, Perry J, Bouatia-Naji N, et al.
Nat Commun
. 2021 Jan;
12(1):24.
PMID: 33402679
Differences between sexes contribute to variation in the levels of fasting glucose and insulin. Epidemiological studies established a higher prevalence of impaired fasting glucose in men and impaired glucose tolerance...
6.
Kenny D, Plichta D, Shungin D, Koppel N, Hall A, Fu B, et al.
Cell Host Microbe
. 2020 Jun;
28(2):245-257.e6.
PMID: 32544460
The human microbiome encodes extensive metabolic capabilities, but our understanding of the mechanisms linking gut microbes to human metabolism remains limited. Here, we focus on the conversion of cholesterol to...
7.
Shungin D, Haworth S, Divaris K, Agler C, Kamatani Y, Lee M, et al.
Nat Commun
. 2019 Jun;
10(1):2773.
PMID: 31235808
Dental caries and periodontitis account for a vast burden of morbidity and healthcare spending, yet their genetic basis remains largely uncharacterized. Here, we identify self-reported dental disease proxies which have...
8.
Lloyd-Price J, Arze C, Ananthakrishnan A, Schirmer M, Avila-Pacheco J, Poon T, et al.
Nature
. 2019 May;
569(7758):655-662.
PMID: 31142855
Inflammatory bowel diseases, which include Crohn's disease and ulcerative colitis, affect several million individuals worldwide. Crohn's disease and ulcerative colitis are complex diseases that are heterogeneous at the clinical, immunological,...
9.
Divaris K, Shungin D, Rodriguez-Cortes A, Basta P, Roach J, Cho H, et al.
Methods Mol Biol
. 2019 Mar;
1922:525-548.
PMID: 30838598
Early childhood caries (ECC) is a biofilm-mediated disease. Social, environmental, and behavioral determinants as well as innate susceptibility are major influences on its incidence; however, from a pathogenetic standpoint, the...
10.
Agler C, Shungin D, Ferreira Zandona A, Schmadeke P, Basta P, Luo J, et al.
Methods Mol Biol
. 2019 Mar;
1922:493-509.
PMID: 30838596
Oral health and disease are known to be influenced by complex interactions between environmental (e.g., social and behavioral) factors and innate susceptibility. Although the exact contribution of genomics and other...