Dmitry A Stetsenko
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Explore the profile of Dmitry A Stetsenko including associated specialties, affiliations and a list of published articles.
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46
Citations
256
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Recent Articles
1.
Klabenkova K, Zhdanova P, Burakova E, Bizyaev S, Fokina A, Stetsenko D
Int J Mol Sci
. 2024 Feb;
25(4).
PMID: 38396686
Staudinger reaction on the solid phase between an electronodeficit organic azide, such as sulfonyl azide, and the phosphite triester formed upon phosphoramidite coupling is a convenient method for the chemical...
2.
Proskurina A, Ruzanova V, Ritter G, Efremov Y, Mustafin Z, Lashin S, et al.
J Biomed Res
. 2023 May;
37(3):194-212.
PMID: 37161885
To overcome immune tolerance to cancer, the immune system needs to be exposed to a multi-target action intervention. Here, we investigated the activating effect of CpG oligodeoxynucleotides (ODNs), mesyl phosphoramidate...
3.
Kupryushkin M, Filatov A, Mironova N, Patutina O, Chernikov I, Chernolovskaya E, et al.
Mol Ther Nucleic Acids
. 2022 Jan;
27:211-226.
PMID: 34976439
Antisense gapmer oligonucleotides containing phosphoryl guanidine (PG) groups, e.g., 1,3-dimethylimidazolidin-2-imine, at three to five internucleotidic positions adjacent to the 3' and 5' ends were prepared via the Staudinger chemistry, which...
4.
Dyrkheeva N, Filimonov A, Luzina O, Orlova K, Chernyshova I, Kornienko T, et al.
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34768766
Tyrosyl-DNA phosphodiesterase 1 (TDP1) catalyzes the cleavage of the phosphodiester bond between the tyrosine residue of topoisomerase 1 (TOP1) and the 3' phosphate of DNA in the single-strand break generated...
5.
Ruzanova V, Proskurina A, Ritter G, Efremov Y, Nikolin V, Popova N, et al.
Anticancer Res
. 2021 Jul;
41(7):3371-3387.
PMID: 34230133
Background/aim: We compared the therapeutic efficacy of two recently developed experimental anticancer technologies: 1) in situ vaccination based on local immunotherapy with CpG oligonucleotides and anti-OX40 antibodies to activate antitumor...
6.
Hammond S, Sergeeva O, Melnikov P, Goli L, Stoodley J, Zatsepin T, et al.
Nucleic Acid Ther
. 2021 May;
31(3):190-200.
PMID: 33989066
A series of 2'-deoxy and novel 2'--methyl and 2'--(2-methoxyethyl) (2'-MOE) oligonucleotides with internucleotide methanesulfonyl (mesyl, μ) or 1-butanesulfonyl (busyl, β) phosphoramidate groups has been synthesized for evaluation as potential splice-switching...
7.
Patutina O, Gaponova Miroshnichenko S, Senkova A, Savin I, Gladkikh D, Burakova E, et al.
Proc Natl Acad Sci U S A
. 2020 Dec;
117(51):32370-32379.
PMID: 33288723
The design of modified oligonucleotides that combine in one molecule several therapeutically beneficial properties still poses a major challenge. Recently a new type of modified mesyl phosphoramidate (or µ-) oligonucleotide...
8.
Su Y, Edwards P, Stetsenko D, Filichev V
Chembiochem
. 2020 Apr;
21(17):2455-2466.
PMID: 32281223
A quaternary ammonium butylsulfonyl phosphoramidate group (N+) was designed to replace all the phosphates in a G-rich oligodeoxynucleotide d(TG T), resulting in a formally charge-neutral zwitterionic N+TG T sequence. We...
9.
Skvortsova Y, Salina E, Burakova E, Bychenko O, Stetsenko D, Azhikina T
Front Pharmacol
. 2019 Oct;
10:1049.
PMID: 31632266
The worldwide spread of multidrug-resistant strains prompted the development of new strategies to combat tuberculosis, one of which is antisense therapy based on targeting bacterial mRNA by oligonucleotide derivatives. However,...
10.
Lomzov A, Kupryushkin M, Shernyukov A, Nekrasov M, Dovydenko I, Stetsenko D, et al.
Data Brief
. 2019 Jul;
25:104148.
PMID: 31312699
This article presents new data on the properties of the diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotides d(TpCp*A) [1,2]. The data include information on isolation, identification, treatment with snake venom...