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Dmitriy Sonkin

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Citations 7021
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Recent Articles
11.
Danos A, Krysiak K, Barnell E, Coffman A, McMichael J, Kiwala S, et al.
Genome Med . 2019 Nov; 11(1):76. PMID: 31779674
Manually curated variant knowledgebases and their associated knowledge models are serving an increasingly important role in distributing and interpreting variants in cancer. These knowledgebases vary in their level of public...
12.
Sonkin D, Thomas A, Teicher B
Lung Cancer Manag . 2019 Oct; 8(2):LMT13. PMID: 31645891
Until recently, small cell lung cancer (SCLC) was described as SCLC and SCLC variant, based upon cellular morphology and loss of neuroendocrine markers in the SCLC variant. However, based on...
13.
Palmisano A, Krushkal J, Li M, Fang J, Sonkin D, Wright G, et al.
Methods Mol Biol . 2019 Sep; 2055:649-678. PMID: 31502173
In recent years, cancer immunotherapy has emerged as a highly promising approach to treat patients with cancer, as the patient's own immune system is harnessed to attack cancer cells. However,...
14.
Ghandi M, Huang F, Jane-Valbuena J, Kryukov G, Lo C, McDonald 3rd E, et al.
Nature . 2019 May; 569(7757):503-508. PMID: 31068700
Large panels of comprehensively characterized human cancer models, including the Cancer Cell Line Encyclopedia (CCLE), have provided a rigorous framework with which to study genetic variants, candidate targets, and small-molecule...
15.
Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin A, Kim S, et al.
Nature . 2018 Dec; 565(7738):E5-E6. PMID: 30559381
No abstract available.
16.
Monks A, Zhao Y, Hose C, Hamed H, Krushkal J, Fang J, et al.
Cancer Res . 2018 Oct; 78(24):6807-6817. PMID: 30355619
: The intracellular effects and overall efficacies of anticancer therapies can vary significantly by tumor type. To identify patterns of drug-induced gene modulation that occur in different cancer cell types,...
17.
Danos A, Ritter D, Wagner A, Krysiak K, Sonkin D, Micheel C, et al.
Hum Mutat . 2018 Oct; 39(11):1721-1732. PMID: 30311370
Harmonization of cancer variant representation, efficient communication, and free distribution of clinical variant-associated knowledge are central problems that arise with increased usage of clinical next-generation sequencing. The Clinical Genome Resource...
18.
Walsh M, Ritter D, Kesserwan C, Sonkin D, Chakravarty D, Chao E, et al.
Hum Mutat . 2018 Oct; 39(11):1542-1552. PMID: 30311369
In its landmark paper about Standards and Guidelines for the Interpretation of Sequence Variants, the American College of Medical Genetics and Genomics (ACMG), and Association for Molecular Pathology (AMP) did...
19.
Madhavan S, Ritter D, Micheel C, Rao S, Roy A, Sonkin D, et al.
AMIA Jt Summits Transl Sci Proc . 2018 Jun; 2017:152-159. PMID: 29888062
In the last 3-5 years, there has been a rapid increase in clinical use of next generation sequencing (NGS) based cancer molecular diagnostic (MolDx) testing to develop better treatment plans...
20.
Madhavan S, Ritter D, Micheel C, Rao S, Roy A, Sonkin D, et al.
Pac Symp Biocomput . 2017 Dec; 23:247-258. PMID: 29218886
A growing number of academic and community clinics are conducting genomic testing to inform treatment decisions for cancer patients (1). In the last 3-5 years, there has been a rapid...