Dirk Van Den Boom
Overview
Explore the profile of Dirk Van Den Boom including associated specialties, affiliations and a list of published articles.
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Articles
62
Citations
3155
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0
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Recent Articles
1.
Ehrich M, Sagaser K, Porreco R, Bellesheim D, Patil A, Shulman L, et al.
Am J Obstet Gynecol
. 2023 Mar;
229(1):75-76.
PMID: 36921913
No abstract available.
2.
Flory A, Kruglyak K, Tynan J, McLennan L, Rafalko J, Fiaux P, et al.
PLoS One
. 2022 Apr;
17(4):e0266623.
PMID: 35471999
Cancer is the leading cause of death in dogs, yet there are no established screening paradigms for early detection. Liquid biopsy methods that interrogate cancer-derived genomic alterations in cell-free DNA...
3.
Chibuk J, Flory A, Kruglyak K, Leibman N, Nahama A, Dharajiya N, et al.
Front Vet Sci
. 2021 Apr;
8:664718.
PMID: 33834049
Cancer is the leading cause of death in dogs, in part because many cases are identified at an advanced stage when clinical signs have developed, and prognosis is poor. Increased...
4.
Dharajiya N, Grosu D, Farkas D, McCullough R, Almasri E, Sun Y, et al.
Clin Chem
. 2017 Oct;
64(2):329-335.
PMID: 28982650
Background: Noninvasive prenatal testing (NIPT) uses cell-free DNA (cfDNA) as an analyte to detect copy-number alterations in the fetal genome. Because maternal and fetal cfDNA contributions are comingled, changes in...
5.
Ellison C, Sun Y, Hogg G, Fox J, Tao H, McCarthy E, et al.
Clin Chem
. 2016 Oct;
62(12):1621-1629.
PMID: 27694391
Background: Current methods for noninvasive prenatal testing (NIPT) ascertain fetal aneuploidies using either direct counting measures of DNA fragments from specific genomic regions or relative measures of single nucleotide polymorphism...
6.
Ehrich M, Grosu D, Van Den Boom D, Tynan J
Am J Obstet Gynecol
. 2016 Jun;
215(4):534-5.
PMID: 27316785
No abstract available.
7.
Van Den Boom D, Ehrich M, Kim S
N Engl J Med
. 2015 Dec;
373(26):2584.
PMID: 26699184
No abstract available.
8.
Kim S, Hannum G, Geis J, Tynan J, Hogg G, Zhao C, et al.
Prenat Diagn
. 2015 May;
35(8):810-5.
PMID: 25967380
Objective: This study introduces a novel method, referred to as SeqFF, for estimating the fetal DNA fraction in the plasma of pregnant women and to infer the underlying mechanism that...
9.
Jensen T, Kim S, Zhu Z, Chin C, Gebhard C, Lu T, et al.
Genome Biol
. 2015 Apr;
16:78.
PMID: 25886572
Background: Circulating cell-free fetal DNA has enabled non-invasive prenatal fetal aneuploidy testing without direct discrimination of the maternal and fetal DNA. Testing may be improved by specifically enriching the sample...
10.
Zhao C, Tynan J, Ehrich M, Hannum G, McCullough R, Saldivar J, et al.
Clin Chem
. 2015 Feb;
61(4):608-16.
PMID: 25710461
Background: The development of sequencing-based noninvasive prenatal testing (NIPT) has been largely focused on whole-chromosome aneuploidies (chromosomes 13, 18, 21, X, and Y). Collectively, they account for only 30% of...