Dirk Sombroek
Overview
Explore the profile of Dirk Sombroek including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
173
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0
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Recent Articles
1.
Bitomsky N, Conrad E, Moritz C, Polonio-Vallon T, Sombroek D, Schultheiss K, et al.
Proc Natl Acad Sci U S A
. 2013 Oct;
110(45):E4203-12.
PMID: 24145406
Excessive genome damage activates the apoptosis response. Protein kinase HIPK2 is a key regulator of DNA damage-induced apoptosis. Here, we deciphered the molecular mechanism of HIPK2 activation and show its...
2.
Winter M, Sombroek D, Dauth I, Moehlenbrink J, Scheuermann K, Crone J, et al.
Nat Cell Biol
. 2008 Jun;
10(7):812-24.
PMID: 18536714
The tumour suppressor HIPK2 is an important regulator of cell death induced by DNA damage, but how its activity is regulated remains largely unclear. Here we demonstrate that HIPK2 is...
3.
Zschiedrich I, Hardeland U, Krones-Herzig A, Diaz M, Vegiopoulos A, Muggenburg J, et al.
Blood
. 2008 May;
112(2):264-76.
PMID: 18469200
Inflammatory responses represent a hallmark of numerous pathologies including sepsis, bacterial infection, insulin resistance, and malign obesity. Here we describe an unexpected coactivator function for the nuclear receptor interacting protein...