Kathrin Schultheiss
Overview
Explore the profile of Kathrin Schultheiss including associated specialties, affiliations and a list of published articles.
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Articles
2
Citations
54
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Recent Articles
1.
Bitomsky N, Conrad E, Moritz C, Polonio-Vallon T, Sombroek D, Schultheiss K, et al.
Proc Natl Acad Sci U S A
. 2013 Oct;
110(45):E4203-12.
PMID: 24145406
Excessive genome damage activates the apoptosis response. Protein kinase HIPK2 is a key regulator of DNA damage-induced apoptosis. Here, we deciphered the molecular mechanism of HIPK2 activation and show its...
2.
Crone J, Glas C, Schultheiss K, Moehlenbrink J, Krieghoff-Henning E, Hofmann T
Cancer Res
. 2011 Jan;
71(6):2350-9.
PMID: 21248071
HIPK2 activates the apoptotic arm of the DNA damage response by phosphorylating tumor suppressor p53 at serine 46. Unstressed cells keep HIPK2 levels low through targeted polyubiquitination and subsequent proteasomal...