Dirk Menche
Overview
Explore the profile of Dirk Menche including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
100
Citations
592
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Guhlke M, Herbst J, Nguyen T, Schneider A, Dickschat J, Menche D
Org Lett
. 2025 Mar;
27(10):2317-2322.
PMID: 40033929
The central hexaene core of the labile polyene antibiotic bacillaene bearing three -configured olefins was prepared with excellent geometrical purity by an iterative cross-coupling strategy, involving improved syntheses of bimetallic...
2.
Meringdal J, Bade L, Bendas G, Menche D
ChemMedChem
. 2024 Feb;
19(9):e202400055.
PMID: 38351738
Inspired by potent antiproliferative xanthone natural products and so far limited examples of derived bioactive agents, a structure activity study of architecturally novel types of xanthones is reported. Their preparation...
3.
Gnirck A, Philipp M, Waterholter A, Wunderlich M, Shaikh N, Adamiak V, et al.
Nat Commun
. 2023 Nov;
14(1):7372.
PMID: 37968302
Mucosal-associated invariant T (MAIT) cells have been implicated in various inflammatory diseases of barrier organs, but so far, their role in kidney disease is unclear. Here we report that MAIT...
4.
Schrempp M, Wagner R, Gleich H, Gansauer A, Menche D
Org Lett
. 2023 Nov;
25(45):8089-8094.
PMID: 37930187
A versatile titanocene-catalyzed radical allyl transfer reaction on epoxides is reported. Epoxide opening occurs regioselectively at the more hindered side, and variously substituted allyl sulfone may be coupled to this...
5.
Wollnitzke P, Wagner R, Afsar S, Werner M, Geschold R, Muller C, et al.
Bioorg Med Chem Lett
. 2023 Aug;
94:129464.
PMID: 37634760
Simplified analogues of the myxobacterial polyketide ajudazol were obtained by synthesis and evaluated for their biological activities. Potent simplified 5-lipoxygenase inhibitors were identified. Moreover, strong antiproliferative and apoptotic activities were...
6.
Arndts K, Kegele J, Massarani A, Ritter M, Wagner T, Pfarr K, et al.
PLoS Negl Trop Dis
. 2023 Aug;
17(8):e0011503.
PMID: 37535695
Previous studies have described the association of onchocerciasis (caused by Onchocerca volvulus) with epilepsy, including nodding syndrome, although a clear etiological link is still missing. Cases are found in different...
7.
Braun C, Wingen L, Menche D
Nat Prod Rep
. 2023 Jul;
40(11):1718-1734.
PMID: 37492928
Covering: the literature up to 2022This study discusses various synthetic strategies for the synthesis of lipid II, the pivotal bacterial cell wall precursor. In detail, it examines different solution phase...
8.
Babczyk A, Menche D
J Am Chem Soc
. 2023 May;
145(20):10974-10979.
PMID: 37162233
The total synthesis of the potent polyene macrolide antibiotic pentamycin was accomplished by an expedient strategy involving a highly stereoselective assembly of the polyol segment in combination with an adventurous...
9.
Gao X, Menche D
Chem Asian J
. 2022 Dec;
18(3):e202201193.
PMID: 36541601
Two novel tandem sequences for stereoselective synthesis of elaborate hydropyranones are reported. The first one relies on an aldol-lactonization procedure of a chiral enolate with an unprotected aldehyde, while the...
10.
Estevez-Gallego J, Alvarez-Bernad B, Pera B, Wullschleger C, Raes O, Menche D, et al.
Structure
. 2022 Dec;
31(1):88-99.e5.
PMID: 36462501
Taxanes are microtubule-stabilizing agents used in the treatment of many solid tumors, but they often involve side effects affecting the peripheral nervous system. It has been proposed that this could...