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Dirk Lang

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Articles 24
Citations 296
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Recent Articles
1.
Ncube S, Nagarajan A, Lang D, Sinkala M, Burmeister C, Serala K, et al.
Mol Cancer Res . 2024 Sep; 23(1):20-32. PMID: 39264104
Breast cancer is the second leading cause of death in women globally, and it remains a health burden due to poor therapy response, cancer cell drug resistance, and the debilitating...
2.
Mungra N, Nsole Biteghe F, Huysamen A, Hardcastle N, Bunjun R, Naran K, et al.
Mol Pharm . 2024 Jul; 21(8):4098-4115. PMID: 39047292
Triple-negative breast cancer (TNBC) is the deadliest form of breast cancer with limited treatment options. The persistence of highly tumorigenic CD44-expressing subpopulation referred to as cancer stem cells (CSCs), endowed...
3.
Mungra N, Biteghe F, Malindi Z, Huysamen A, Karaan M, Hardcastle N, et al.
J Cancer Res Clin Oncol . 2023 Jul; 149(13):12203-12225. PMID: 37432459
Purpose: Triple-negative breast cancer (TNBC) is phenotypic of breast tumors lacking expression of the estrogen receptor (ER), the progesterone receptor (PgR), and the human epidermal growth factor receptor 2 (HER2)....
4.
Huysamen A, Fadeyi O, Mayuni G, Dogbey D, Mungra N, Biteghe F, et al.
ACS Omega . 2023 Feb; 8(4):4026-4037. PMID: 36743041
Antibody-drug conjugates (ADCs) are bifunctional molecules combining the targeting potential of monoclonal antibodies with the cancer-killing ability of cytotoxic drugs. This simple yet intelligently designed system directly addresses the lack...
5.
Carse S, Lang D, Katz A, Schafer G
Viruses . 2021 Dec; 13(12). PMID: 34960740
Understanding and modulating the early steps in oncogenic Human Papillomavirus (HPV) infection has great cancer-preventative potential, as this virus is the etiological agent of virtually all cervical cancer cases and...
6.
Kotze L, Beltran C, Lang D, Loxton A, Cooper S, Meiring M, et al.
mSphere . 2021 Jul; 6(4):e0055221. PMID: 34287004
Tuberculous granulomas that develop in response to Mycobacterium tuberculosis (M. tuberculosis) infection are highly dynamic entities shaped by the host immune response and disease kinetics. Within this microenvironment, immune cell...
7.
Gray C, OHagan K, Lorenzo-Redondo R, Olivier A, Amu S, Chigorimbo-Murefu N, et al.
Mucosal Immunol . 2019 Oct; 13(1):118-127. PMID: 31619762
We compared outer and inner foreskin tissue from adolescent males undergoing medical male circumcision to better understand signals that increase HIV target cell availability in the foreskin. We measured chemokine...
8.
Schonfeldt-Lecuona C, Gahr M, Schutz S, Lang D, Pajonk F, Connemann B, et al.
Fortschr Neurol Psychiatr . 2017 Aug; 85(7):400-409. PMID: 28768348
 Psychiatric emergencies (PE) in preclinical emergency medical services are about 5 - 10 % of all emergencies and represent often a source of difficulties in handling for the non-psychiatric professional...
9.
Gahr M, Eller J, Cabanis M, Hiemke C, Freudenmann R, Connemann B, et al.
J Subst Abuse Treat . 2017 Jan; 74:7-15. PMID: 28132703
To study drug safety and the reporting behavior of adverse drug reactions (ADR) related to agents used for opioid replacement therapy (ORT) we conducted a cross-sectional questionnaire-based telephone survey among...
10.
Weissflog G, Honig K, Gundel H, Lang D, Niederwieser D, Dohner H, et al.
Support Care Cancer . 2016 Dec; 25(5):1445-1454. PMID: 27987096
Purpose: The way couples mutually cope with hematologic cancer is likely to influence their levels of supportive care needs (SCN). Therefore, this study evaluated the levels of dyadic coping (DC)...