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Dirk Keene

Explore the profile of Dirk Keene including associated specialties, affiliations and a list of published articles. Areas
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Citations 95
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Recent Articles
1.
Uneri A, McArdle C, Deng Z, Barth S, Keene D, Craft S, et al.
J Alzheimers Dis . 2024 Nov; 102(3):763-777. PMID: 39610285
Background: RNA-binding proteins (RBPs) modulate the synaptic proteome and are instrumental in maintaining synaptic homeostasis. Moreover, aberrant expression of an RBP in a disease state would have deleterious downstream effects...
2.
Kalhor K, Chen C, Lee H, Cai M, Nafisi M, Que R, et al.
bioRxiv . 2023 Aug; PMID: 37645998
In situ transcriptomic techniques promise a holistic view of tissue organization and cell-cell interactions. Recently there has been a surge of multiplexed RNA in situ techniques but their application to...
3.
Huynh H, Kuch K, Orquillas A, Forrest K, Barahona-Carrillo L, Keene D, et al.
Clin Chem . 2023 Jun; 69(7):734-745. PMID: 37279935
Background: APOE genotype is associated with Alzheimer disease. Thus, the concentration of apolipoprotein E (apoE) isoforms in cerebrospinal fluid (CSF) could be altered in dementia. However, conflicting results have been...
4.
Darvas M, Keene D, Ladiges W
Pathobiol Aging Age Relat Dis . 2019 May; 9(1):1616994. PMID: 31143415
No abstract available.
5.
Ebbert M, Jensen T, Jansen-West K, Sens J, Reddy J, Ridge P, et al.
Genome Biol . 2019 May; 20(1):97. PMID: 31104630
Background: The human genome contains "dark" gene regions that cannot be adequately assembled or aligned using standard short-read sequencing technologies, preventing researchers from identifying mutations within these gene regions that...