Dirk F van Helden
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Explore the profile of Dirk F van Helden including associated specialties, affiliations and a list of published articles.
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46
Citations
680
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Recent Articles
1.
Hashitani H, Takeya M, van Helden D
J Physiol
. 2024 Apr;
PMID: 38607187
During emission, the first phase of ejaculation, smooth muscle in organs of the male reproductive tract (MRT) vigorously contract upon sympathetic nerve excitation to expel semen consisting of sperm and...
2.
Walweel K, Beard N, van Helden D, Laver D
J Gen Physiol
. 2023 Jun;
155(8).
PMID: 37279522
Dantrolene is a neutral hydantoin that is clinically used as a skeletal muscle relaxant to prevent overactivation of the skeletal muscle calcium release channel (RyR1) in response to volatile anesthetics....
3.
4.
Tamanna S, Morosin S, Delforce S, van Helden D, Lumbers E, Pringle K
Mol Cell Endocrinol
. 2022 Feb;
547:111609.
PMID: 35202745
Placental renin-angiotensin system (RAS) components; prorenin, angiotensinogen, and angiotensin (Ang) II type 1 receptor (ATR) are upregulated during syncytialisation. This study examined whether angiotensin-converting enzyme (ACE), ACE2 and neprilysin (NEP)...
5.
Mitsui R, Hashitani H, Lang R, van Helden D
Pflugers Arch
. 2021 Oct;
473(12):1925-1938.
PMID: 34596752
Here we investigate mechanisms underlying spontaneous phasic contractions (SPCs) and sympathetic control of contractility in the rat epididymis, a long tubular duct involved in transportation and maturation of sperm. Longitudinal...
6.
Tamanna S, Clifton V, Rae K, van Helden D, Lumbers E, Pringle K
Front Physiol
. 2021 Jun;
12:692761.
PMID: 34093245
[This corrects the article DOI: 10.3389/fphys.2020.590787.].
7.
Ferdoushi A, Griffin N, Marsland M, Xu X, Faulkner S, Gao F, et al.
Sci Rep
. 2021 Apr;
11(1):7390.
PMID: 33795769
Pancreatic cancer is a highly aggressive malignancy characterized by poor survival, recurrence after surgery and resistance to therapy. Nerves infiltrate the microenvironment of pancreatic cancers and contribute to tumor progression,...
8.
Pineda S, Nikolova-Krstevski V, Leimena C, Atkinson A, Altekoester A, Cox C, et al.
Circ Genom Precis Med
. 2021 Feb;
14(2):e003144.
PMID: 33629867
Background: encodes the α-subunit of the large-conductance Ca-activated K channel, K1.1, and lies within a linkage interval for atrial fibrillation (AF). Insights into the cardiac functions of K1.1 are limited,...
9.
Tamanna S, Clifton V, Rae K, van Helden D, Lumbers E, Pringle K
Front Physiol
. 2020 Oct;
11:590787.
PMID: 33101066
Introduction: An imbalance in angiotensin (Ang) peptides could contribute to the pathophysiology of preeclampsia (PE) and poor fetal growth. Methods: We measured maternal plasma levels of Ang peptides and converting...
10.
Ferdoushi A, Li X, Griffin N, Faulkner S, Jamaluddin M, Gao F, et al.
Front Oncol
. 2020 Sep;
10:1601.
PMID: 32984024
Schwann cells (SCs), the glial component of peripheral nerves, have been identified as promoters of pancreatic cancer (PC) progression, but the molecular mechanisms are unclear. In the present study, we...