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Dipanwita Basu

Explore the profile of Dipanwita Basu including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 448
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Recent Articles
1.
Patnaik S, Basu D, Southall N, Dehdashti S, Wan K, Zheng W, et al.
Bioorg Med Chem Lett . 2019 Mar; 29(9):1113-1119. PMID: 30852083
Nonstructural protein 1 (NS1) plays a crucial function in the replication, spread, and pathogenesis of influenza virus by inhibiting the host innate immune response. Here we report the discovery and...
2.
Frieman M, Basu D, Matthews K, Taylor J, Jones G, Pickles R, et al.
PLoS One . 2011 Dec; 6(12):e28479. PMID: 22164298
Severe acute respiratory coronavirus (SARS-CoV) emerged in 2002, resulting in roughly 8000 cases worldwide and 10% mortality. The animal reservoirs for SARS-CoV precursors still exist and the likelihood of future...
3.
Hagan K, Reedy C, Uchimoto M, Basu D, Engel D, Landers J
Lab Chip . 2010 Dec; 11(5):957-61. PMID: 21152489
We describe the first miniaturized device capable of the front-end sample preparation essential for detecting RNA-based infectious agents. The microfluidic device integrates sample purification and reverse transcription PCR (RT-PCR) amplification...
4.
Walkiewicz M, Basu D, Jablonski J, Mario Geysen H, Engel D
J Gen Virol . 2010 Oct; 92(Pt 1):60-70. PMID: 20881091
Influenza virus non-structural protein 1 (NS1) is the centrepiece of the viral response to the host interferon (IFN) system. NS1 has been demonstrated previously to be a potential therapeutic target...
5.
Basu D, Walkiewicz M, Frieman M, Baric R, Auble D, Engel D
J Virol . 2008 Dec; 83(4):1881-91. PMID: 19052087
The innate immune system guards against virus infection through a variety of mechanisms including mobilization of the host interferon system, which attacks viral products mainly at a posttranscriptional level. The...
6.
Basu D, Le J, Zakharova T, Mallery E, Szymanski D
Proc Natl Acad Sci U S A . 2008 Mar; 105(10):4044-9. PMID: 18308939
During morphogenesis, the actin cytoskeleton mediates cell-shape change in response to growth signals. In plants, actin filaments organize the cytoplasm in regions of polarized growth, and the filamentous arrays can...
7.
Basu D, Le J, El-Essal S, Huang S, Zhang C, Mallery E, et al.
Plant Cell . 2005 Jan; 17(2):502-24. PMID: 15659634
In a plant cell, a subset of actin filaments function as a scaffold that positions the endomembrane system and acts as a substrate on which organelle motility occurs. Other actin...
8.
El-Assal S, Le J, Basu D, Mallery E, Szymanski D
Curr Biol . 2004 Aug; 14(15):1405-9. PMID: 15296760
In migrating cells, the actin filament nucleation activity of ARP2/3 is an essential component of dynamic cell shape change and motility. In response to signals from the small GTPase Rac1,...
9.
Basu D, El-Assal S, Le J, Mallery E, Szymanski D
Development . 2004 Aug; 131(17):4345-55. PMID: 15294869
The WAVE complex is an essential regulator of actin-related protein (ARP) 2/3-dependent actin filament nucleation and cell shape change in migrating cells. Although the composition of the WAVE complex is...
10.
El-Assal S, Le J, Basu D, Mallery E, Szymanski D
Plant J . 2004 Apr; 38(3):526-38. PMID: 15086808
Arabidopsis trichomes are unicellular, branched structures that have highly constrained requirements for the cytoskeleton. The 'distorted group' genes function downstream from microtubule-based branch initiation, and are required during the actin-dependent...