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Dimitrios Mathios

Explore the profile of Dimitrios Mathios including associated specialties, affiliations and a list of published articles. Areas
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Articles 52
Citations 1640
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Recent Articles
1.
Hernandez-Rovira M, Connor M, Osorio R, Russler-Germain E, Schmidt R, Johnson G, et al.
Front Oncol . 2025 Mar; 15:1510439. PMID: 40052132
Background And Importance: Atypical teratoid rhabdoid tumors (ATRTs) are typically aggressive pediatric tumors with a median survival of 11 months. Due to the paucity of cases in adults, the clinical...
2.
Medina J, Annapragada A, Lof P, Short S, Bartolomucci A, Mathios D, et al.
Cancer Discov . 2024 Sep; 15(1):105-118. PMID: 39345137
There is an unmet need for effective ovarian cancer screening and diagnostic approaches that enable earlier-stage cancer detection and increased overall survival. We have developed a high-performing accessible approach that...
3.
Bobeff E, Mathios D, Longo D, Estin J, Joshua S, Tabaee A, et al.
J Neurol Surg B Skull Base . 2024 Sep; 85(5):517-525. PMID: 39228881
 Pedicled nasoseptal flap (NSF) placement is a critical component of skull base reconstruction after endoscopic endonasal approaches (EEAs). The effectiveness of NSF reuse has not been thoroughly studied. Prior reports...
4.
Noe M, Mathios D, Annapragada A, Koul S, Foda Z, Medina J, et al.
Nat Commun . 2024 Aug; 15(1):6690. PMID: 39107309
Circulating cell-free DNA (cfDNA) is emerging as an avenue for cancer detection, but the characteristics of cfDNA fragmentation in the blood are poorly understood. We evaluate the effect of DNA...
5.
Fu Y, Xu Y, Liu W, Zhang J, Wang F, Jian Q, et al.
EClinicalMedicine . 2024 Jul; 73:102697. PMID: 39022798
Background: Current surveillance modalities of osteosarcoma relapse exhibit limited sensitivity and specificity. Although circulating tumor DNA (ctDNA) has been established as a biomarker of minimal residual disease (MRD) in many...
6.
Korte B, Mathios D
Int J Mol Sci . 2024 Apr; 25(8). PMID: 38673779
Meningiomas are tumors of the central nervous system that vary in their presentation, ranging from benign and slow-growing to highly aggressive. The standard method for diagnosing and classifying meningiomas involves...
7.
Annapragada A, Niknafs N, White J, Bruhm D, Cherry C, Medina J, et al.
Sci Transl Med . 2024 Mar; 16(738):eadj9283. PMID: 38478628
Genetic changes in repetitive sequences are a hallmark of cancer and other diseases, but characterizing these has been challenging using standard sequencing approaches. We developed a de novo kmer finding...
8.
Mathios D, Bobeff E, Longo D, Nilchian P, Estin J, Schwartz A, et al.
J Neurosurg . 2023 Sep; 140(3):677-687. PMID: 37657097
Objective: The lateral transorbital approach (LTOA) is a relatively new minimal access skull base approach suited for addressing paramedian pathology of the anterior and middle fossa. The authors define target...
9.
Bruhm D, Mathios D, Foda Z, Annapragada A, Medina J, Adleff V, et al.
Nat Genet . 2023 Jul; 55(8):1301-1310. PMID: 37500728
Somatic mutations are a hallmark of tumorigenesis and may be useful for non-invasive diagnosis of cancer. We analyzed whole-genome sequencing data from 2,511 individuals in the Pan-Cancer Analysis of Whole...
10.
Mathios D, Bobeff E, Longo D, Tabaee A, Anand V, Godfrey K, et al.
Oper Neurosurg (Hagerstown) . 2023 May; 25(2):168-175. PMID: 37163719
Background: The repair of lateral sphenoid sinus cerebrospinal fluid leaks is routinely accomplished through the use of the endonasal endoscopic approach (EEA) with a transpterygoidal extension. This approach can incur...