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Diletta Dolfini

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Articles 42
Citations 734
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Recent Articles
1.
Dolfini D, Imbriano C, Mantovani R
Cell Death Differ . 2024 Sep; 32(2):195-206. PMID: 39327506
NF-Y is a conserved sequence-specific trimeric Transcription Factor -TF- binding to the CCAAT element. We review here the role(s) in development, from pre-implantation embryo to terminally differentiated tissues, by rationalizing...
2.
Magni S, Sbarberi R, Dolfini D, Nigro L, Binelli A
Aquat Toxicol . 2024 Jul; 273:107032. PMID: 39068809
Million tons of tires become waste every year, and the so-called End-of-Life Tires (ELTs) are ground into powder (ELT-dp; size < 0.8 mm) and granules (ELT-dg; 0.8 < size <...
3.
Ronzio M, Bernardini A, Taglietti V, Ceribelli M, Donati G, Gallo A, et al.
Genomics . 2024 Jul; 116(5):110895. PMID: 39025317
NF-Y is a Transcription Factor that regulates transcription through binding to the CCAAT-box. To understand its strategy, we analyzed 16 ChIP-seq datasets from human and mouse cells. Shared loci, mostly...
4.
Dolfini D, Gnesutta N, Mantovani R
Biochim Biophys Acta Rev Cancer . 2024 Feb; 1879(2):189082. PMID: 38309445
NF-Y is a Transcription Factor (TF) targeting the CCAAT box regulatory element. It consists of the NF-YB/NF-YC heterodimer, each containing an Histone Fold Domain (HFD), and the sequence-specific subunit NF-YA....
5.
Da Dalt L, Moregola A, Svecla M, Pedretti S, Fantini F, Ronzio M, et al.
Cardiovasc Res . 2023 Nov; 119(18):2917-2929. PMID: 37922889
Aims: Mitochondria are plastic organelles that continuously undergo biogenesis, fusion, fission, and mitophagy to control cellular energy metabolism, calcium homeostasis, hormones, sterols, and bile acids (BAs) synthesis. Here, we evaluated...
6.
Rigillo G, Belluti S, Campani V, Ragazzini G, Ronzio M, Miserocchi G, et al.
Cancer Lett . 2023 Jun; 567:216262. PMID: 37307894
Aberrant splicing events are associated with colorectal cancer (CRC) and provide new opportunities for tumor diagnosis and treatment. The expression of the splice variants of NF-YA, the DNA binding subunit...
7.
Londero M, Gallo A, Cattaneo C, Ghilardi A, Ronzio M, Del Giacco L, et al.
Cell Death Dis . 2023 Jan; 14(1):65. PMID: 36707502
NF-Y is a trimeric transcription factor whose binding site -the CCAAT box- is enriched in cancer-promoting genes. The regulatory subunit, the sequence-specificity conferring NF-YA, comes in two major isoforms, NF-YA...
8.
Bezzecchi E, Pagani G, Forte B, Percio S, Zaffaroni N, Dolfini D, et al.
Front Cell Dev Biol . 2022 Jul; 10:909097. PMID: 35784469
Aside serving as host gene for , transcribes for a chromatin-associated long noncoding RNA (lncRNA) able to restrain the differentiation of prostate basal cells, thus being reannotated as (Long Epithelial...
9.
Bernardini A, Gallo A, Gnesutta N, Dolfini D, Mantovani R
Genomics . 2022 May; 114(4):110390. PMID: 35589059
NF-Y is a trimeric pioneer Transcription Factor (TF) whose target sequence -the CCAAT box- is present in ~25% of mammalian promoters. We reconstruct the phylogenetic history of the regulatory NF-YA...
10.
Gallo A, Ronzio M, Bezzecchi E, Mantovani R, Dolfini D
Sci Rep . 2021 Dec; 11(1):23764. PMID: 34887475
NF-Y is a pioneer transcription factor-TF-formed by the Histone-like NF-YB/NF-YC subunits and the regulatory NF-YA. It binds to the CCAAT box, an element enriched in promoters of genes overexpressed in...