Diletta Dolfini
Overview
Explore the profile of Diletta Dolfini including associated specialties, affiliations and a list of published articles.
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42
Citations
734
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Recent Articles
11.
Belluti S, Semeghini V, Rigillo G, Ronzio M, Benati D, Torricelli F, et al.
J Exp Clin Cancer Res
. 2021 Nov;
40(1):362.
PMID: 34782004
Background: Approaches based on expression signatures of prostate cancer (PCa) have been proposed to predict patient outcomes and response to treatments. The transcription factor NF-Y participates to the progression from...
12.
Rigillo G, Basile V, Belluti S, Ronzio M, Sauta E, Ciarrocchi A, et al.
Nat Commun
. 2021 Oct;
12(1):6013.
PMID: 34650038
The transcription factor NF-Y promotes cell proliferation and its activity often declines during differentiation through the regulation of NF-YA, the DNA binding subunit of the complex. In stem cell compartments,...
13.
Bezzecchi E, Bernardini A, Ronzio M, Miccolo C, Chiocca S, Dolfini D, et al.
Cancers (Basel)
. 2021 Jul;
13(12).
PMID: 34208636
NF-Y is the CCAAT-binding trimer formed by the histone fold domain (HFD), NF-YB/NF-YC and NF-YA. The CCAAT box is generally prevalent in promoters of "cancer" genes. We reported the overexpression...
14.
Ronzio M, Bernardini A, Pavesi G, Mantovani R, Dolfini D
PLoS Comput Biol
. 2020 Dec;
16(12):e1008488.
PMID: 33370256
NF-Y is a trimeric Transcription Factor -TF- which binds with high selectivity to the conserved CCAAT element. Individual ChIP-seq analysis as well as ENCODE have progressively identified locations shared by...
15.
Bezzecchi E, Ronzio M, Mantovani R, Dolfini D
Int J Mol Sci
. 2020 Dec;
21(23).
PMID: 33271832
NF-Y is a pioneer trimeric transcription factor formed by the Histone Fold Domain (HFD) NF-YB/NF-YC subunits and NF-YA. Three subunits are required for DNA binding. CCAAT-specificity resides in NF-YA and...
16.
Nardone V, Chaves-Sanjuan A, Lapi M, Airoldi C, Saponaro A, Pasqualato S, et al.
Cells
. 2020 Nov;
9(11).
PMID: 33138093
NF-Y is a transcription factor (TF) comprising three subunits (NF-YA, NF-YB, NF-YC) that binds with high specificity to the CCAAT sequence, a widespread regulatory element in gene promoters of prosurvival,...
17.
Libetti D, Bernardini A, Sertic S, Messina G, Dolfini D, Mantovani R
Cells
. 2020 Mar;
9(3).
PMID: 32214056
NF-YA, the regulatory subunit of the trimeric transcription factor (TF) NF-Y, is regulated by alternative splicing (AS) generating two major isoforms, "long" (NF-YAl) and "short" (NF-YAs). Muscle cells express NF-YAl....
18.
Ronzio M, Zambelli F, Dolfini D, Mantovani R, Pavesi G
Front Genet
. 2020 Mar;
11:72.
PMID: 32153638
Chromatin immunoprecipitation followed by next-generation sequencing (ChIP-Seq) has opened new avenues of research in the genome-wide characterization of regulatory DNA-protein interactions at the genetic and epigenetic level. As a consequence,...
19.
Bezzecchi E, Ronzio M, Semeghini V, Andrioletti V, Mantovani R, Dolfini D
Genes (Basel)
. 2020 Feb;
11(2).
PMID: 32075093
The trimeric transcription factor (TF) NF-Y regulates the CCAAT box, a DNA element enriched in promoters of genes overexpressed in many types of cancer. The regulatory NF-YA is present in...
20.
Bezzecchi E, Ronzio M, Dolfini D, Mantovani R
Genes (Basel)
. 2019 Nov;
10(11).
PMID: 31744190
The CCAAT box is recognized by the trimeric transcription factor NF-Y, whose NF-YA subunit is present in two major splicing isoforms, NF-YAl ("long") and NF-YAs ("short"). Little is known about...