Diego Colombo
Overview
Explore the profile of Diego Colombo including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
281
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Recent Articles
1.
Ciceri S, Fassi E, Vezzoli V, Bonomi M, Colombo D, Ferraboschi P, et al.
Eur J Med Chem
. 2024 Sep;
279:116903.
PMID: 39342681
Gonadotropin-releasing hormone (GnRH) is the main regulator of the reproductive system, acting on gonadotropic cells by binding to the GnRH1 receptor (GnRH1R). Traditionally, therapies targeting this receptor have relied on...
2.
Iannone M, Valtorta S, Stucchi S, Altomonte S, Turolla E, Vino E, et al.
EJNMMI Radiopharm Chem
. 2024 Jun;
9(1):50.
PMID: 38904859
Background: In the last decade the development of new PSMA-ligand based radiopharmaceuticals for the imaging and therapy of prostate cancer has been a highly active and important area of research....
3.
Zuccolo M, Orsini G, Quaglia M, Mirra L, Corno C, Carenini N, et al.
Org Biomol Chem
. 2023 Aug;
21(32):6572-6587.
PMID: 37526931
-Oxyamides of bioactive anionic glycoglycerolipids based on 2--β-D-glucosylglycerol were efficiently prepared. However, the oxidation step of the primary hydroxyl group of the glucose moiety in the presence of the -oxyamide...
4.
Ciceri S, Colombo D, Fassi E, Ferraboschi P, Grazioso G, Grisenti P, et al.
Molecules
. 2023 May;
28(9).
PMID: 37175271
Elagolix sodium salt is the first marketed orally active non-peptide gonadotropin-releasing hormone receptor antagonist (GnRHR-ant) for the management of hormone dependent diseases, such as endometriosis and uterine fibroids. Despite its...
5.
The deubiquitinase USP8 regulates ovarian cancer cell response to cisplatin by suppressing apoptosis
Corno C, Darcy P, Bagnoli M, Paolini B, Costantino M, Carenini N, et al.
Front Cell Dev Biol
. 2022 Dec;
10:1055067.
PMID: 36578788
The identification of therapeutic approaches to improve response to platinum-based therapies is an urgent need for ovarian carcinoma. Deubiquitinases are a large family of ubiquitin proteases implicated in a variety...
6.
Costantino M, Corno C, Colombo D, Perego P
Front Pharmacol
. 2022 Jun;
13:889816.
PMID: 35685638
Curcumin and related compounds are known for the large spectrum of activities. The chemical features of these compounds are important for their biological effects with a key role for the...
7.
Conte G, Costabile G, Baldassi D, Rondelli V, Bassi R, Colombo D, et al.
ACS Appl Mater Interfaces
. 2022 Feb;
14(6):7565-7578.
PMID: 35107987
Inhaled siRNA therapy has a unique potential for treatment of severe lung diseases, such as cystic fibrosis (CF). Nevertheless, a drug delivery system tackling lung barriers is mandatory to enhance...
8.
Colombo D, Gatti L, Sjostrand L, Carenini N, Costantino M, Corna E, et al.
Biochem Pharmacol
. 2022 Jan;
197:114900.
PMID: 34995485
Deubiquitinases (DUBs) mediate the removal of ubiquitin from diverse proteins that participate in the regulation of cell survival, DNA damage repair, apoptosis and drug resistance. Previous studies have shown an...
9.
Mori M, Villa S, Ciceri S, Colombo D, Ferraboschi P, Meneghetti F
Molecules
. 2021 Dec;
26(23).
PMID: 34885662
The elucidation of the structure of enzymes and their complexes with ligands continues to provide invaluable insights for the development of drugs against many diseases, including bacterial infections. After nearly...
10.
Ciceri S, Colombo D, Ferraboschi P, Grisenti P, Iannone M, Mori M, et al.
Steroids
. 2021 Oct;
176:108928.
PMID: 34655596
Vecuronium bromide (Piperidinium, 1-[(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-, bromide; Norcuron®) has been extensively used in anesthesiology practice as neuromuscular blocking agent since its launch on the market in 1982. However, a detailed crystallographic and...