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Diane C Maestas

Explore the profile of Diane C Maestas including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Potter R, Maestas D, Cimino D, Prossnitz E
J Immunol . 2006 Apr; 176(9):5418-25. PMID: 16622009
Adaptation, defined as the diminution of receptor signaling in the presence of continued or repeated stimulation, is critical to cellular function. G protein-coupled receptors (GPCRs) undergo multiple adaptive processes, including...
2.
Vines C, Revankar C, Maestas D, LaRusch L, Cimino D, Kohout T, et al.
J Biol Chem . 2003 Aug; 278(43):41581-4. PMID: 12947104
Arrestins mediate phosphorylation-dependent desensitization, internalization, and initiation of signaling cascades for the majority of G protein-coupled receptors (GPCRs). Many GPCRs undergo agonist-mediated internalization through arrestin-dependent mechanisms, wherein arrestin serves as...
3.
Shi M, Bennett T, Cimino D, Maestas D, Foutz T, Gurevich V, et al.
Biochemistry . 2003 Jun; 42(24):7283-93. PMID: 12809484
G protein-coupled receptors (GPCRs) must constantly compete for interactions with G proteins, kinases, and arrestins. To evaluate the interactions of these proteins with GPCRs in greater detail, we generated a...
4.
Vines C, Xue M, Maestas D, Cimino D, Prossnitz E
J Immunol . 2002 Dec; 169(12):6760-6. PMID: 12471107
One of the major functions of the N-formyl peptide receptor (FPR) is to mediate leukocyte degranulation. Phosphorylation of the C-terminal domain of the FPR is required for receptor internalization and...