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Dhvani Sandip Vora

Explore the profile of Dhvani Sandip Vora including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Kaushal S, Gupta S, Shefrin S, Vora D, Kaul S, Sundar D, et al.
Cancers (Basel) . 2024 Oct; 16(20). PMID: 39456564
Upregulation of stress chaperone Mortalin has been closely linked to the malignant transformation of cells, tumorigenesis, the progression of tumors to highly aggressive stages, metastasis, drug resistance, and relapse. Various...
2.
Vora D, Bhandari S, Sundar D
Methods . 2024 Apr; 226:120-126. PMID: 38641083
The CRISPR/Cas9 genome editing technology has transformed basic and translational research in biology and medicine. However, the advances are hindered by off-target effects and a paucity in the knowledge of...
3.
Yadav S, Vora D, Sundar D, Dhanjal J
Comput Struct Biotechnol J . 2023 Dec; 23:165-173. PMID: 38146434
Cognate target identification for T-cell receptors (TCRs) is a significant barrier in T-cell therapy development, which may be overcome by accurately predicting TCR interaction with peptide-bound major histocompatibility complex (pMHC)....
4.
Kesarwani P, Vora D, Sundar D
ACS Omega . 2023 Dec; 8(48):45578-45588. PMID: 38075777
Targeted nucleases are widely used for altering the specific location of the genome with precision. The endonucleases facilitate efficient genome editing via designing a guide RNA (gRNA) consisting of a...
5.
Vora D, Yadav S, Sundar D
Biomolecules . 2023 May; 13(4). PMID: 37189388
CRISPR/Cas9 technology is capable of precisely editing genomes and is at the heart of various scientific and medical advances in recent times. The advances in biomedical research are hindered because...
6.
Vora D, Kalakoti Y, Sundar D
Methods Mol Biol . 2022 Oct; 2553:285-323. PMID: 36227550
Protein interactions play a critical role in all biological processes, but experimental identification of protein interactions is a time- and resource-intensive process. The advances in next-generation sequencing and multi-omics technologies...
7.
Vora D, Verma Y, Sundar D
Biomolecules . 2022 Aug; 12(8). PMID: 36009017
The reprogrammable CRISPR/Cas9 genome editing tool's growing popularity is hindered by unwanted off-target effects. Efforts have been directed toward designing efficient guide RNAs as well as identifying potential off-target threats,...
8.
Vora D, Jaiswal A, Sundar D
J Biomol Struct Dyn . 2022 Jul; 41(13):6178-6190. PMID: 35882048
The clustered regularly interspersed short palindromic repeats (CRISPR) and its associated nuclease (Cas9) offers a unique and easily reprogrammable system for editing eukaryotic genomes. Cas9 is guided to the target...