Dhanansayan Shanmuganayagam
Overview
Explore the profile of Dhanansayan Shanmuganayagam including associated specialties, affiliations and a list of published articles.
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52
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883
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Recent Articles
1.
Chen M, Sheng Z, Wei R, Zhang B, Kim H, Wu H, et al.
Theranostics
. 2025 Jan;
15(3):815-827.
PMID: 39776794
Ultrasound-induced thermal strain imaging (US-TSI) is a promising ultrasound imaging modality that has been demonstrated in preclinical studies to identify a lipid-rich necrotic core of an atherosclerotic plaque. However, human...
2.
De La Cruz K, Townsend E, Cheong J, Salamzade R, Liu A, Sandstrom S, et al.
Fungal Genet Biol
. 2024 May;
173:103898.
PMID: 38815692
The skin and its microbiome function to protect the host from pathogen colonization and environmental stressors. In this study, using the Wisconsin Miniature Swine™ model, we characterize the porcine skin...
3.
Liu A, Cheong J, Hassan S, Wielgat M, Meudt J, Townsend E, et al.
Wound Repair Regen
. 2024 May;
32(5):675-685.
PMID: 38775411
Porcine models are frequently used for burn healing studies; however, factors including anatomic location and lack of standardised wound methods can impact the interpretation of wound data. The objectives of...
4.
Anand R, Layer J, Heja D, Hirose T, Lassiter G, Firl D, et al.
Nature
. 2023 Oct;
622(7982):393-401.
PMID: 37821590
Recent human decedent model studies and compassionate xenograft use have explored the promise of porcine organs for human transplantation. To proceed to human studies, a clinically ready porcine donor must...
5.
McLean D, Meudt J, Lopez Rivera L, Schomberg D, Pavelec D, Duellman T, et al.
Front Oncol
. 2023 Oct;
13:1253659.
PMID: 37817770
Neurofibromatosis Type 1 (NF1) is one of the most common genetically inherited disorders that affects 1 in 3000 children annually. Clinical manifestations vary widely but nearly always include the development...
6.
Flakus M, Wuschner A, Wallat E, Graham M, Shao W, Shanmuganayagam D, et al.
Sci Rep
. 2023 Jun;
13(1):9377.
PMID: 37296169
Imaging biomarkers can assess disease progression or prognoses and are valuable tools to help guide interventions. Particularly in lung imaging, biomarkers present an opportunity to extract regional information that is...
7.
Flakus M, Wuschner A, Wallat E, Shao W, Meudt J, Shanmuganayagam D, et al.
Med Phys
. 2023 Mar;
50(10):6366-6378.
PMID: 36999913
Background: Biomarkers estimating local lung ventilation have been derived from computed tomography (CT) imaging using various image acquisition and post-processing techniques. CT-ventilation biomarkers have potential clinical use in functional avoidance...
8.
Flakus M, Wuschner A, Wallat E, Shao W, Shanmuganayagam D, Christensen G, et al.
Front Physiol
. 2023 Mar;
14:1040028.
PMID: 36866176
To quantify the impact of image noise on CT-based lung ventilation biomarkers calculated using Jacobian determinant techniques. Five mechanically ventilated swine were imaged on a multi-row CT scanner with acquisition...
9.
Wuschner A, Flakus M, Wallat E, Reinhardt J, Shanmuganayagam D, Christensen G, et al.
Front Physiol
. 2022 Nov;
13:1008526.
PMID: 36324304
Vessel segmentation in the lung is an ongoing challenge. While many methods have been able to successfully identify vessels in normal, healthy, lungs, these methods struggle in the presence of...
10.
Wuschner A, Flakus M, Wallat E, Reinhardt J, Shanmuganayagam D, Christensen G, et al.
J Pers Med
. 2022 Aug;
12(8).
PMID: 36013203
Recent functional lung imaging studies have presented evidence of an “indirect effect” on perfusion damage, where regions that are unirradiated or lowly irradiated but that are supplied by highly irradiated...