Mattison J Flakus
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Explore the profile of Mattison J Flakus including associated specialties, affiliations and a list of published articles.
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14
Citations
45
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Recent Articles
1.
Carrizales J, Flakus M, Fairbourn D, Shao W, Gerard S, Bayouth J, et al.
Med Phys
. 2024 Nov;
52(2):1096-1107.
PMID: 39540716
Background: Four-dimensional computed tomography (4DCT) is an es sential tool in radiation therapy. However, the 4D acquisition process may cause motion artifacts which can obscure anatomy and distort functional measurements...
2.
Tegtmeier R, Clouser E, Laughlin B, Santos Toesca D, Flakus M, Bashir S, et al.
J Appl Clin Med Phys
. 2024 Jul;
25(9):e14464.
PMID: 39031902
Purpose: To assess the practicality of employing a commercial knowledge-based planning tool (RapidPlan) to generate adapted intact prostate and prostate bed volumetric modulated arc therapy (VMAT) plans on iterative cone-beam...
3.
Baschnagel A, Flakus M, Wallat E, Wuschner A, Chappell R, Bayliss R, et al.
Int J Radiat Oncol Biol Phys
. 2024 Feb;
119(5):1393-1402.
PMID: 38387810
Purpose: To determine whether 4-dimensional computed tomography (4DCT) ventilation-based functional lung avoidance radiation therapy preserves pulmonary function compared with standard radiation therapy for non-small cell lung cancer (NSCLC). Methods And...
4.
Flakus M, Wuschner A, Wallat E, Graham M, Shao W, Shanmuganayagam D, et al.
Sci Rep
. 2023 Jun;
13(1):9377.
PMID: 37296169
Imaging biomarkers can assess disease progression or prognoses and are valuable tools to help guide interventions. Particularly in lung imaging, biomarkers present an opportunity to extract regional information that is...
5.
Flakus M, Wuschner A, Wallat E, Shao W, Meudt J, Shanmuganayagam D, et al.
Med Phys
. 2023 Mar;
50(10):6366-6378.
PMID: 36999913
Background: Biomarkers estimating local lung ventilation have been derived from computed tomography (CT) imaging using various image acquisition and post-processing techniques. CT-ventilation biomarkers have potential clinical use in functional avoidance...
6.
Flakus M, Wuschner A, Wallat E, Shao W, Shanmuganayagam D, Christensen G, et al.
Front Physiol
. 2023 Mar;
14:1040028.
PMID: 36866176
To quantify the impact of image noise on CT-based lung ventilation biomarkers calculated using Jacobian determinant techniques. Five mechanically ventilated swine were imaged on a multi-row CT scanner with acquisition...
7.
Flakus M, Kent S, Wallat E, Wuschner A, Tennant E, Yadav P, et al.
Radiother Oncol
. 2023 Feb;
182:109553.
PMID: 36813178
Purpose: To identify metrics of radiation dose delivered to highly ventilated lung that are predictive of radiation-induced pneumonitis. Methods And Materials: A cohort of 90 patients with locally advanced non-small...
8.
Wallat E, Wuschner A, Flakus M, Gerard S, Christensen G, Reinhardt J, et al.
Med Phys
. 2023 Feb;
50(5):3199-3209.
PMID: 36779695
Background: Functional lung avoidance radiation therapy (RT) is a technique being investigated to preferentially avoid specific regions of the lung that are predicted to be more susceptible to radiation-induced damage....
9.
Wuschner A, Flakus M, Wallat E, Reinhardt J, Shanmuganayagam D, Christensen G, et al.
Front Physiol
. 2022 Nov;
13:1008526.
PMID: 36324304
Vessel segmentation in the lung is an ongoing challenge. While many methods have been able to successfully identify vessels in normal, healthy, lungs, these methods struggle in the presence of...
10.
Wuschner A, Flakus M, Wallat E, Reinhardt J, Shanmuganayagam D, Christensen G, et al.
J Pers Med
. 2022 Aug;
12(8).
PMID: 36013203
Recent functional lung imaging studies have presented evidence of an “indirect effect” on perfusion damage, where regions that are unirradiated or lowly irradiated but that are supplied by highly irradiated...